Treatment | Strain | CONT | CAST | CAST + T |
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Testosterone (ng/ml) | SHR | 1.88 ± 0.52 | 0.05 ± 0.60 | 12.9 ± 0.70 |
 | WKY | 1.08 ± 0.52 | 0.04 ± 0.70 | 11.0 ± 0.78 |
Norepinephrine (pg/ml) | SHR | 970.5 ± 88.4*** | 481.5 ± 50.4** | 762.2 ± 53.8* |
 | WKY | 569.5 ± 28.1 | 415.5 ± 97.3 | 644.9 ± 74.6 |
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aCAST, castrate; CAST + T, castrate plus testosterone; CONT, control; NE, norepinephrine; SHR: spontaneously hypertensive rat; T: testosterone; WKY: Wistar Kyoto. Data are means ± SEM. Plasma T was unaltered between SHR and WKY T-manipulated groups. Plasma NE was significantly higher in SHR CONT males than in WKY CONT males (***P < 0.001). Plasma NE was decreased in SHR CAST compared to CONT (**P < 0.01) and increased compared to CAST + T (*P < 0.05).