Table 1 Genes altered in the spleen of males compared to females using false discovery rate analysis.
GenBank | Gene | Gene name | Fold increase | P value |
|---|---|---|---|---|
Higher expression in uninfected males | ||||
NM_012011 | Eif2s3y | Eukaryotic translation initiation factor 2 | 53.88 | 3.3 × 10-22 |
NM_012008 | Ddx3y | DEAD box polypeptide, Y-linked | 38.95 | 1.8 × 10-20 |
NM_009484 | Uty | Ubiquitously transcribed tetratricopeptide repeat gene | 23.87 | 2.3 × 10-17 |
NM_011419 | Jarid1d | Jumonji, AT rich interactive domain | 12.21 | 3.5 × 10-16 |
Lower expression in uninfected males | ||||
NR_001463 | Xist | Inactive X-specific transcripts | -64.65 | 4.2 × 10-20 |
NM_009483 | Utx | Ubiquitously transcribed tetratricopeptide repeat gene | -1.45 | 1.7 × 10-7 |
NM_012011 | Eif2s3x | Eukaryotic transl. initiation factor 2 | -1.33 | 1.2 × 10-5 |
Higher expression in infected males | ||||
NM_012011 | Eif2s3y | Eukaryotic transl. initiation factor 2 | 51.01 | 4.1 × 10-22 |
NM_012008 | Ddx3y | DEAD box polypeptide, Y-linked | 39.24 | 1.7 × 10-20 |
NM_009484 | Uty | Ubiquitously transcribed tetratricopeptide repeat gene | 24.99 | 1.8 × 10-17 |
NM_011419 | Jarid1d | Jumonji, AT rich interactive domain | 12.21 | 3.5 × 10-16 |
Lower expression in infected males | ||||
NR_001463 | Xist | Inactive X-specific transcripts | -62.49 | 4.8 × 10-20 |
NM_009483 | Utx | Ubiquitously transcribed tetratricopeptide repeat gene | -1.64 | 3.8 × 10-9 |
NM_012010 | Eif2s3x | Eukaryotic translation initiation factor 2 | -1.33 | 1.1 × 10-5 |
NM_011861 | Pacsin1 | Protein kinase C, casein kinase | -1.24 | 2.1 × 10-6 |