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Fig. 5 | Biology of Sex Differences

Fig. 5

From: Sex- and age-related differences in renal and cardiac injury and senescence in stroke-prone spontaneously hypertensive rats

Fig. 5

Cellular senescence markers in hearts of male and female SHRSP rats. a Senescence-associated β-galactosidase (SA-β-gal) activity within the heart (% positive staining). b γH2AX positive (+) cells per field of view (FOV; 1.5 mm2). c Representative images of SA-β-gal activity in hearts from all groups. Scale = 50 µm. d γH2AX immunostaining in the vasculature, interstitium and cardiomyocytes in hearts collected from 8.5 Mo male SHRSP rats. Scale = 50 µm. Values represent mean ± SEM; N = 8–11/group. Data analysed via two-way ANOVA

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