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Table 1 Sociodemographic and clinical variables at the baseline for each group (LPDf; LPDm; RPDf; RPDm; HCf; HCm)

From: Moderating effects of uric acid and sex on cognition and psychiatric symptoms in asymmetric Parkinson’s disease

 

LPDf (n = 74)

LPDm (n = 105)

RPDf (n = 71)

RPDm (n = 163)

HCf (n = 70)

HCm (n = 126)

K–W/Chi2

Age in years (mean ± SD)

60.16 (± 10.71)

60.53 (± 9.55)

61.13 (± 8.35)

62.79 (± 9.75)

59.37 (± 11.70)

61.62 (± 10.92)

0.103

Education in years (mean ± SD)

15.19 (± 3.20)

15.58 (± 2.80)

15.31 (± 3.02)

15.74 (± 3.00)

15.49 (± 2.72)

16.35 (± 2.95)

0.088

Race [White; Black; Asian; other] (in %)

91.89; 0; 2.70; 5.41

91.43; 2.86; 3.81; 1.90

90.14; 2.81; 1.41; 5.63

95.71; 0; 0; 4.29

91.43; 4.29; 1.43; 2.86

92.86; 5.56; 0; 1.59

0.031

Age of onset in years (mean ± SD)

58.13 (± 10.94)

58.61 (± 9.90)

58.87 (± 8.73)

60.84 (± 9.93)

0.070

Age at diagnostic in years (mean ± SD)

59.58 (± 10.68)

60.05 (± 9.60)

60.52 (± 8.36)

62.22 (± 9.68)

0.078

Initial symptom (at diagnosis)

 Resting tremor

No: 17.57%

No: 26.67%

No: 25.35%

No: 17.79%

No: 100.00%

No: 100.00%

0.230

Yes: 82.43%

Yes: 73.33%

Yes: 74.65%

Yes: 82.21%

Yes: 0.00%

Yes: 0.00%

 Rigidity

No: 29.73%

No: 19.05%

No: 32.39%

No: 20.86%

No: 100.00%

No: 100.00%

0.095

Yes: 70.27%

Yes: 80.95%

Yes: 67.61%

Yes: 79.14%

Yes: 0.00%

Yes: 0.00%

 Bradykinesia

No: 16.22%

No: 11.43%

No: 22.54%

No: 20.25%

No: 100.00%

No: 100.00%

0.186

Yes: 83.78%

Yes: 88.57%

Yes: 77.46%

Yes: 79.75%

Yes: 0.00%

Yes: 0.00%

 Postural instability

No: 91.89%

No: 92.38%

No: 94.37%

No: 94.48%

No: 100.00%

No: 100.00%

0.833

Yes: 8.11%

Yes: 7.62%

Yes: 5.63%

Yes: 5.52%

Yes: 0.00%

Yes: 0.00%

 Other

No: 79.73%

No: 87.62%

No: 81.69%

No: 84.66%

No: 100.00%

No: 100.00%

0.500

Yes: 20.27%

Yes: 12.38%

Yes: 18.31%

Yes: 15.34%

Yes: 0.00%

Yes: 0.00%

  1. f female, HC healthy controls, LPD patients with Parkinson’s disease (PD) who exhibit predominantly left-sided motor symptoms, m male, RPD patients with PD who exhibit predominantly right-sided motor symptoms, K–W Kruskal–Wallis test, M–W Mann–Whitney U test, SD standard deviation