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Fig. 6 | Biology of Sex Differences

Fig. 6

From: Sex differences in learning and performing the Go/NoGo tasks

Fig. 6

Overall performances for reversal Go/NoGo task. a Success rates for individual stage. The success rates were calculated for each reversal stage based on the total number of animals remaining in that stage. No significant differences were detected (Paired t-test, p = 0.22). b Accumulating time needed for mastering each reversal stage (mean ± SEM). No statistically significant differences were detected for stage R1. The female rats need longer time from stages R2–R4 (Student’s t-test, p = 0.04 for stage R2–R4). c Time needed for mastering individual reversal stages (mean ± SEM). No statistically significant differences were detected for stages R1, R3 and R4. The female rats needed longer time to master stage R2 than the male rats (Student’s t-test, p = 0.02 for stage R2). d Comparisons of correct NoGo rates between reversal stages and stages G3–G9. The correct NoGo rates of male rats in the reversal stages were significantly higher than both male rats of stages G3–9 and female rats of Stages R1–R4 (p = 1.75 × 10–5 and p = 0.003, respectively). e Comparisons of correct Go rates between reversal stages and stages G3–G9. The correct Go rates of both male and female rats in the reversal stages were significantly decreased than those of stages G3–G9 (p = 6.18 × 10–7 and p = 0.005 for male and female rats, respectively). f Comparison of NH time for male and female rats in the reversal stages. The NH time was significantly shorter for the female rats than that of the male rats (p = 6.08 × 10–51 with an effect size of 1.49). g–h Comparison of RTs and MTs for male and female rats in the reversal stages. No significant differences were detected for RTs (p = 5.98 × 10–100 with an effect size of 0.98) and MTs (p = 3.56 × 10–8 with an effect size of 0.29). i–j Comparison of RTs for male and female rats between the reversal stages and stage G9. The RTs of reversal stages were significantly longer than that of stage G9 for male (p = 6.03 × 10–100 with an effect size of − 1.32) and female (p = 6.28 × 10–26 with an effect size of 0.06) rats, respectively. k–l Comparison of MTs for male and female rats between the reversal stages and stage G9. The MTs of reversal stages were significantly longer than that of stage G9 for male (p = 1.27 × 10–75 with an effect size of − 0.86) and female (p = 1.27 × 10–75 with an effect size of − 0.41) rats, respectively. Two-way ANOVA with repeated measures and post hoc Holm–Sidak tests were used for d ~ e. Wilcoxon signed rank test was used for f–l

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