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Fig. 5 | Biology of Sex Differences

Fig. 5

From: Lipidomic landscape of circulating extracellular vesicles isolated from adolescents exposed to ethanol intoxication: a sex difference study

Fig. 5

Summary of lipids with significant abundance in humans by class annotation in negative and positive-ion mode. A The super class percentages (inner) show the number of lipids each super class represents in the total significant lipids. The main class percentages (outer) show the number of lipids each main class represents in its corresponding super class. B Number of significant lipids in the sub classes. The bar charts indicate the number of significant lipids in the sub classes, and the color corresponds to the main class. Comparisons used: EEF (ethanol effects in females), EEM (ethanol effects in males), and SEI (sex–ethanol interaction). Sub-class lipid abbreviations: Cer_AS, ceramide α-hydroxy fatty acid-sphingosine; Cer_NDS, ceramide non-hydroxy fatty acid-dihydrosphingosine; Cer_NP, ceramide non-hydroxy fatty acid-phytosphingosine; Cer_ADS, ceramide α-hydroxy fatty acid-dihydrosphingosine; Cer_AP, ceramide α-hydroxy fatty acid-phytosphingosine; Cer_NS, ceramide non-hydroxy fatty acid-sphingosine; HexCer_NS, glucosylCeramide/HexosylCeramidesnon-hydroxyfatty acid-sphingosine; HexCer_NDS, glucosylCeramide/HexosylCeramidesnon-hydroxyfatty acid-dihydrosphingosine; SM, sphingomyelin; FA, fatty acid; FAHFA, fatty acid ester of hydroxyl fatty acid; PA, phosphatidic acid; LPC, lyso-phosphatidylcholine; PC, phosphatidylcholine; PC-O, etherphosphatidylcholine (EtherPC); PE, phosphatidylethanolamine; PE-O, etherphosphatidylethanolamine (EtherPE); PI, phosphatidylinositol; DAG, diacylglycerol; TAG, triacylglycerol (TG); Chol. esters, cholesterol esters

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