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Fig. 2 | Biology of Sex Differences

Fig. 2

From: Aerobic exercise improves executive functions in females, but not males, without the BDNF Val66Met polymorphism

Fig. 2

Total time taken to complete the Trail Making Test (B–A) in seconds at trial completion, adjusted for baseline Montreal Cognitive Assessment and baseline Trail Making Test (B–A) scores. A 6-month aerobic training program significantly improved performance in female brain-derived neurotrophic factor (BDNF) Val/Val carriers and decreased performance in male BDNF Val/Val carriers compared with a usual care plus education control program. No difference was seen in female and male Met carriers

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