Fig. 4

Correlation of platelet parameters with liver function tests, metabolic, inflammatory, and sex steroid biomarkers. ALP alkaline phosphatase; ALT alanine aminotransferase; AST aspartate aminotransferase; CRP C-reactive protein; GGT gamma-glutamyltransferase; HbA1c haemoglobin A1c (glycated haemoglobin); HDL high-density lipoprotein; LDL low-density lipoprotein; MPV mean platelet volume; PDW platelet distribution width; SHBG sex hormone binding globulin. Values represent partial Pearson correlation coefficients with adjustment for body mass index, a body shape index, hip index, height, age, weight change (last year), smoking status, alcohol consumption, physical activity, Townsend deprivation index (continuous), time of blood collection (continuous), fasting time (continuous), use of nonsteroidal anti-inflammatory drugs, paracetamol use, and for women, menopausal status, hormone replacement therapy use, oral contraceptives use, and age at the last live birth. Correlation coefficients were calculated in a subset of participants with available all biomarker measurements (94,285 (75.2%) women; 87,702 (76.4%) men)