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Table 5 Sex-specific hazard ratios (HRs) between the number of complications in patients with type 2 diabetes and dementia subtypes*

From: Sex-specific associations between diabetes and dementia: the role of age at onset of disease, insulin use and complications

 

Adjusted HR (95% CI)*

 

All-cause dementia

Alzheimer's disease

Vascular dementia

People with no diabetes at all

Reference

Reference

Reference

All patients with type 2 diabetes

   

 0

2.45 (2.17, 2.78)

2.03 (1.73, 2.38)

3.48 (2.91, 4.15)

 1

4.00 (3.24, 4.94)

3.80 (2.93, 4.93)

4.75 (3.47, 6.49)

 ≥ 2

8.20 (6.21, 10.83)

5.10 (3.33, 7.81)

12.85 (9.04, 18.25)

Female patients with type 2 diabetes

   

 0

2.52 (2.08, 3.05)

2.53 (2.00, 3.18)

2.51 (1.85, 3.42)

 1

3.65 (2.54, 5.25)

3.76 (2.44, 5.81)

3.44 (1.89, 6.27)

 ≥ 2

7.59 (4.39, 13.14)

8.06 (4.17, 15.57)

8.63 (3.84, 19.38)

Male patients with type 2 diabetes

   

 0

2.42 (2.08, 2.81)

1.76 (1.43, 2.16)

4.01 (3.29, 4.89)

 1

4.36 (3.39, 5.61)

3.95 (2.88, 5.43)

5.87 (4.11, 8.37)

 ≥ 2

8.57 (6.24, 11.76)

4.15 (2.40, 7.19)

14.98 (10.24, 21.89)

  1. * All HRs were adjusted for age at last follow-up, race/ethnicity, educational years, income level, physical activity level, leisure activities, body mass index (BMI), smoking status, hypertension status and APOE 4 allele status