| All-cause dementia | Alzheimer's disease | Vascular dementia | ||||||
---|---|---|---|---|---|---|---|---|---|
 | Dementia events (n) | Events per 1000 person-years | Adjusted HR (95% CI)* | Dementia events (n) | Events per 1000 person-years | Adjusted HR (95% CI)* | Dementia events (n) | Events per 1000 person-years | Adjusted HR (95% CI)* |
People with no diabetes at all | 2561 | 0.54 | Reference | 1918 | 0.40 | Reference | 817 | 0.17 | Reference |
All patients with type 2 diabetes | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 With insulin | 153 | 3.96 | 4.71 (3.91, 5.66) | 82 | 2.11 | 3.64 (2.83, 4.68) | 94 | 2.42 | 7.23 (5.67, 9.24) |
 Without insulin | 409 | 2.25 | 2.50 (2.21, 2.82) | 240 | 1.32 | 2.12 (1.81, 2.48) | 208 | 1.14 | 3.32 (2.78, 3.97) |
 Ratio of HR (With/Without insulin) |  |  | 1.54 (1.00, 2.37) |  |  | 1.22 (0.67, 2.22) |  |  | 1.92 (1.06, 3.48) |
Female patients with type 2 diabetes | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 With insulin | 52 | 3.40 | 3.64 (2.60, 5.11) | 34 | 2.22 | 3.75 (2.45, 5.73) | 24 | 1.56 | 3.80 (2.33, 6.20) |
 Without insulin | 254 | 3.78 | 2.28 (1.86, 2.78) | 134 | 1.99 | 2.44 (1.91, 3.10) | 148 | 2.20 | 1.97 (1.41, 2.74) |
 Ratio of HR (With/Without insulin) |  |  | 1.84 (1.26, 2.68) |  |  | 1.77 (1.11, 2.81) |  |  | 2.19 (1.23, 3.88) |
Male patients with type 2 diabetes | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 With insulin | 101 | 4.32 | 4.54 (3.52, 5.86) | 48 | 2.05 | 3.30 (2.30, 4.72) | 70 | 2.99 | 7.08 (5.09, 9.83) |
 Without insulin | 155 | 1.35 | 2.39 (2.05, 2.80) | 106 | 0.92 | 1.86 (1.51, 2.30) | 60 | 0.52 | 3.50 (2.82, 4.35) |
 Ratio of HR (With/Without insulin) |  |  | 1.73 (1.32, 2.26) |  |  | 1.60 (1.09, 2.35) |  |  | 1.91 (1.37, 2.65) |