Fig. 3From: Integrated chromatin accessibility and DNA methylation analysis to reveal the critical epigenetic modification and regulatory mechanism in gonadal differentiation of the sequentially hermaphroditic fish, Monopterus albusGene activation with lose of the chromatin accessibility. A DNA methylation and ATAC signal changes over 10-kb promoter region of the differentially expressed genes from cluster 4. B Overlap genes of DMR hypo, ATAC decrease and RNA up-regulated from cluster 4. C Heatmap of the 67 overlap genes expression profile. D Identified candidates of sex-reversal related genes. Red boxes indicate DARs changes during sex reversalBack to article page