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Fig. 3 | Biology of Sex Differences

Fig. 3

From: Integrated chromatin accessibility and DNA methylation analysis to reveal the critical epigenetic modification and regulatory mechanism in gonadal differentiation of the sequentially hermaphroditic fish, Monopterus albus

Fig. 3

Gene activation with lose of the chromatin accessibility. A DNA methylation and ATAC signal changes over 10-kb promoter region of the differentially expressed genes from cluster 4. B Overlap genes of DMR hypo, ATAC decrease and RNA up-regulated from cluster 4. C Heatmap of the 67 overlap genes expression profile. D Identified candidates of sex-reversal related genes. Red boxes indicate DARs changes during sex reversal

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