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Fig. 2 | Biology of Sex Differences

Fig. 2

From: Integrated chromatin accessibility and DNA methylation analysis to reveal the critical epigenetic modification and regulatory mechanism in gonadal differentiation of the sequentially hermaphroditic fish, Monopterus albus

Fig. 2

DNA methylation changes in TSS region activated gene expression. A MA plots for differentially expressed genes during gonadal development. Black dots represent genes with no significantly change. Red and green dots represent significantly up-regulated and down-regulated genes during gonadal development, respectively (P < 0.05). B Gene ontology terms associated with significantly differentially expressed genes. C Different expression profile during the gonadal development. D DNA methylation level over 10-kb region centre and promoter of the differentially expressed genes from cluster 4

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