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Table 2 Relationship between PP and incident diabetes in different models by sex

From: High pulse pressure is associated with an increased risk of diabetes in females but not in males: a retrospective cohort study

PP (mm Hg)

Male (n = 114,972), HR (95% CI)

Female (n = 94,663), HR (95% CI)

Unadjusted

Model 1

Model 2

Unadjusted

Model 1

Model 2

Per 10 mmHg

1.247 (1.207,1.288)

1.056 (1.023,1.090)

0.981 (0.951,1.012)

1.963 (1.873,2.058)

1.248 (1.185,1.315)

1.117 (1.061,1.176)

1st quartile (< 37 mmHg)

Reference

Reference

Reference

Reference

Reference

Reference

2nd quartile (37–43 mmHg)

1.032 (0.912,1.169)

1.030 (0.909,1.166)

0.988 (0.873,1.119)

1.353 (1.071,1.708)

1.147 (0.908,1.450)

1.064 (0.842,1.344)

3rd quartile (44-51 mmHg)

1.185 (1.059,1.327)

1.150 (1.027,1.288)

1.031 (0.921,1.155)

2.493 (2.026,3.068)

1.701 (1.379,2.097)

1.466 (1.189,1.807)

4th quartile (≥ 51 mmHg)

1.636 (1.472,1.818)

1.173 (1.053,1.306)

0.939 (0.843,1.045)

6.533 (5.417,7.879)

2.122 (1.736,2.595)

1.494 (1.225,1.822)

P for trend

 < 0.0001

0.007

0.246

 < 0.0001

 < 0.0001

 < 0.0001

  1. Model 1: Adjusted for age, BMI, smoking, alcohol consumption and family history of diabetes
  2. Model 2: Adjusted for age, BMI, smoking, alcohol consumption, family history of diabetes and FPG
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Biology of Sex Differences

ISSN: 2042-6410

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