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Table 2 Anthropometric characteristics and biochemical parameters of men subjects according to FLI categories (n = 19,362)

From: Sex and age differences in the association of fatty liver index-defined non-alcoholic fatty liver disease with cardiometabolic risk factors: a cross-sectional study

Men characteristics

FLI < 30

FLI 30–59

FLI ≥ 60

*p value

n = 7979 (41.2%)

n = 5986 (30.9%)

n = 5397 (27.9%)

Age (years)

39.32 (10.03)

43.72 (9.57)

42.23 (9.99)

< 0.001a, c

Social class

0.070

 High

2586 (32.4%)

1963 (32.8%)

1667 (26.8%)

 

 Low

5393 (67.6%)

4023 (67.2%)

3730 (69.1%)

Smoking status

< 0.001

 Never

4412 (55.3%)

3149 (52.6%)

2486 (46.1%)

a, b, c

 Former

1053 (13.2%)

1134 (18.9%)

1350 (25.0%)

a, b, c

 Current

2514 (31.5%)

1703 (28.4%)

1561 (28.9%)

a, c

BMI (kg/m2)

23.56 (2.20)

26.99 (2.17)

31.44 (4.10)

< 0.001a, b, c

BMI categories

< 0.001

 Normal weight

6071 (76.1%)

940 (15.7%)

88 (1.6%)

a, b, c

 Overweight

1904 (23.9%)

4573 (76.4%)

1905 (37.0%)

a, b, c

 Obese

4 (0.1%)

473 (7.9%)

3314 (61.4%)

a, b, c

WC (cm)

82.66 (5.99)

90.44 (6.11)

97.85 (6.68)

< 0.001a, b, c

SBP (mmHg)

121.36 (13.86)

126.74 (14.61)

131.99 (16.76)

< 0.001a, b, c

DBP (mmHg)

72.96 (9.74)

77.26 (10.40)

81.25 (11.22)

< 0.001a, b, c

BP categories

< 0.001

 Normal

5352 (67.1%)

2935 (49.0%)

1827 (33.9%)

a, b, c

 Prehypertension

1269 (15.9%)

1187 (19.8%)

983 (18.2%)

a, c

 Hypertension

1358 (17.0%)

1864 (31.1%)

2587 (47.9%)

a, b, c

FPG (mg/dL)

88.82 (16.08)

92.81 (18.33)

99.04 (25.87)

< 0.001a, b, c

Diabetes categories

6919 (86.7%)

4570 (76.3%)

3445 (77.1%)

< 0.001

 Normal

820 (10.3%)

1008 (16.8%)

1207 (22.4%)

a, c

 Prediabetes

240 (3.0%)

408 (6.8%)

745 (13.8%)

a, b, c

 Diabetes

   

a, b, c

GGT (IU/L)

21.90 (11.00)

32.92 (23.33)

52.32 (50.77)

< 0.001a, b, c

AST (IU/L)d

21.41 (9.98)

23.77 (14.48)

27.40 (13.72)

< 0.001a, b, c

ALT (IU/L)e

21.17 (12.59)

30.24 (17.73)

38.57 (22.87)

< 0.001a,b,c

Cholesterol (mg/dL)

185.26 (33.14)

200.95 (35.52)

211.88 (38.68)

< 0.001a, b, c

HDL-cholesterol (mg/dL)

56.21 (10.65)

53.29 (9.79)

50.47 (9.97)

< 0.001a, b, c

TG (mg/dL)

88.32 (34.92)

127.27 (56.92)

191.79 (117.73)

< 0.001a, b, c

Dyslipidemia

< 0.001

 No

7457 (93.5%)

4583 (76.6%)

2772 (51.4%)

a, b, c

 Yes

522 (6.5%)

1403 (23.4%)

2625 (48.6%)

a, b, c

Presence of MetS

52 (0.7%)

768 (12.8%)

2978 (55.2%)

< 0.001a, b, c

REGICOR

< 0.001

 Low risk

4816 (60.4%)

3923 (65.5%)

3133 (58.1%)

a, c

 Moderated risk

476, (6.0%)

901 (15.1%)

1325 (24.6%)

a, b, c

 High risk

25 (0.3%)

80 (1.3%)

138 (2.6%)

a, b, c

 Severe risk

3 (0.0%)

11 (0.2%)

31 (0.6%)

a, b, c

  1. Data are expressed as mean (standard deviation) and as count (percentage)
  2. FLI: fatty liver index; BMI: body mass index; BMI categories: normal weight (BMI 18.5 to 24.9 kg/m2), overweight (BMI 25 to 29.9 kg/m2), obese (BMI ≥ 30 kg/m2). WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; BP: blood pressure; BP categories: normal BP (SBP < 130 and/or DBP < 85 mmHg), prehypertension (SBP 130 to 139 and/or DBP 85 to 89 mmHg), hypertension (SBP ≥ 140 and/or DBP ≥ 90 mmHg and/or with antihypertensive treatment); FPG: fasting plasma glucose; diabetes categories: normal (FPG < 100), prediabetes (FPG 100 to 125), diabetes (FPG > 125 and/or antidiabetic treatment); GGT: γ-glutamyl transpeptidase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; HDL: high-density lipoprotein; TG: triglycerides, dyslipidemia: no (TG < 150 and/or HDL < 40 mg/dL in men, < 46 mg/dL in women), yes (TG ≥ 150 and/or HDL ≥ 40 mg/dL in men, ≥ 46 mg/dL in women); MetS: metabolic syndrome according to the IDF; Framingham-REGICOR: low risk (< 5%), moderate risk (5–9.9%), high risk (10–14.9%), severe risk (> 15%)
  3. *p values obtained by one-way ANOVA for continuous variables or by Chi-square for categorical variables
  4. Post hoc test by Bonferroni: asignificant difference between FLI < 30 and FLI 30–59; bsignificant difference between FLI 30–59 and FLI ≥ 60; csignificant difference between FLI < 30 and FLI ≥ 60
  5. dAST available for n = 12,721 (FLI < 30 n = 5362; FLI 30–59 n = 3866; FLI ≥ 60 n = 3493)
  6. eALT available for n = 19,347 (FLI < 30 n = 7973; FLI 30–59 n = 5980; FLI ≥ 60 n = 5394)
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Biology of Sex Differences

ISSN: 2042-6410

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