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Fig. 3 | Biology of Sex Differences

Fig. 3

From: Chromosomal and gonadal sex drive sex differences in lipids and hepatic gene expression in response to hypercholesterolemia and statin treatment

Fig. 3

Gonadal and chromosomal sex impact gene expression in Apoe–/– FCG liver. MA plot shows mean expression and fold-change of genes with differential expression in A mice with ovaries compared to mice with testes (adjusted P < 0.05, fold-change > 1.25) and B the top 10 significant cellular pathways enriched in the differentially expressed genes (adjusted P < 0.05). MA plot shows mean expression and fold-change of genes with differential expression in C XX mice compared to XY mice (adjusted P < 0.05, fold-change > 1.25) and D the top 10 significant cellular pathways enriched in the differentially expressed genes (adjusted P < 0.05)

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Biology of Sex Differences

ISSN: 2042-6410

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