Fig. 2

Characterization of Apoe^–/– FCG liver RNA-seq dataset. A Principal component analysis of liver RNA-seq data from Apoe^–/– FCG mice fed chow diet without or with simvastatin for 8 wks. B Boxplots representing transformed RNA-seq counts across all 24 liver samples. C The genome-wide distribution of genes found to be differentially regulated by presence of ovaries vs. testes (gonadal DEG), or by presence of XX vs. XY chromosomes (Sex Chr DEG). DEG, differentially expressed genes