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Table 7 Main effects of allopregnanolone:progesterone ratio and sex on smoking session measures that did not show a significant interaction effect in Table 6

From: Effect of progesterone administration in male and female smokers on nicotine withdrawal and neural response to smoking cues: role of progesterone conversion to allopregnanolone

Outcome at final smoking session

Effect of log(allo/prog)

(95% CI)

p value

Effect of sex

[ref: female]

(95% CI)

p value

CO (post–pre)

− 0.65 (− 2.58, 1.27)

0.504

1.18 (− 3.40, 5.75)

0.614

Number of cigarettes

0.04 (− 0.29, 0.37)

0.821

− 0.15 (− 0.87, 0.57)

0.684

Volume smoked (1st cigarette)

− 65.4 (− 232.8, 102.1)

0.444

− 129.1 (− 489.6, 231.5)

0.483

Total volume smoked

369.9 (− 229.0, 968.8)

0.226

− 1030.0 (− 2671.0, 611.1)

0.219

NEQ1 (feel strength of nicotine)

2.81 (− 2.17, 7.79)

0.269

− 0.24 (− 17.84, 17.35)

0.979

NEQ2 (feel “good” effects of nicotine)

8.39 (2.58, 14.20)

0.005a

− 12.03 (− 28.98, 4.93)

0.165

NEQ3 (feel “bad” effects of nicotine)

− 7.13 (− 13.53, − 0.73)

0.029a

14.80 (− 1.05, 30.64)

0.067

NEQ4 (head rush)

− 5.41 (− 14.59, 1.77)

0.125

16.33 (− 4.43, 37.09)

0.123

  1. NEQ Nicotine Effects Questionnaire
  2. aStatistical significance at level p < 0.05