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Fig. 1 | Biology of Sex Differences

Fig. 1

From: Effect of progesterone administration in male and female smokers on nicotine withdrawal and neural response to smoking cues: role of progesterone conversion to allopregnanolone

Fig. 1

Crossover study design. Functional magnetic resonance imaging (fMRI) scans measured neural activation in response to smoking and neutral cues. Participants completed measures of withdrawal symptoms, smoking urges, and mood states before each brain scan. Blood draws measured levels of neurosteroids, such as progesterone and allopregnanolone, after each brain scan. Smoking sessions measured change in carbon monoxide (CO) levels, number of cigarettes smoked, inhalation volume for the first cigarette, total inhalation volume during the session, and subjective nicotine effects at baseline and after a 4-day abstinence

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Biology of Sex Differences

ISSN: 2042-6410

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