Myocytic androgen receptor overexpression does not affect sex differences in adaptation to chronic endurance exercise

Table 2 Sex, HSAAR genotype, and endurance exercise effects on tibialis anterior androgen receptor (AR) protein expression

	Effect	F statistic (df)	Groups		T statistic	P-value
	Effect	F statistic (df)	Mean ± SEM	Mean ± SEM	T statistic	P-value
AR (R.D.)	Sex	F(1,37) = 17.36	F: 3.28 ± 0.69	M: 5.71 ± 1.07	–	< 0.001
	Gene	F(1,37) = 131.44	Tg: 7.83 ± 0.76	WT: 1.16 ± 0.15	–	< 0.001
	Exercise	F(1,37) = 4.68	Ex: 5.12 ± 1.02	Sed: 3.86 ± 0.84	–	< 0.05
	Sex × gene	F(1,37) = 11.45			–	< 0.01
			M-Tg: 10.03 ± 0.79	F-Tg: 5.63 ± 0.88	3.716	< 0.001
			F-WT: 0.93 ± 0.18	F-Tg: 5.63 ± 0.88	− 5.262	< 0.001
			M-WT: 1.39 ± 0.24	F-Tg: 5.63 ± 0.88	− 4.684	< 0.001
			F-WT: 0.93 ± 0.18	M-Tg: 10.03 ± 0.79	− 11.171	< 0.001
			M-WT: 1.39 ± 0.24	M-Tg: 10.03 ± 0.79	− 10.428	< 0.001
			M-WT: 1.39 ± 0.24	F-WT: 0.93 ± 0.18	1.543	n.s

Data expressed as relative density (R.D.). F, female (n = 20); M, male (n = 20); Ex, exercise (n = 20); Sed, sedentary (n = 20); Tg, HSAAR transgenic (n = 20); WT, wild-type (n = 20). Data analyzed using three-way ANOVA with post hoc Tukey HSD for multiple comparisons. Non-significant interactive effects not shown, see Additional file 1: Tables S4 and S5

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