Fig. 4From: Myocytic androgen receptor overexpression does not affect sex differences in adaptation to chronic endurance exerciseHSAAR Tg genotype affects glycolytic myofiber size but not proportion, while sex affects both glycolytic and oxidative myofiber size and proportion across EDL. Visualization of a succinate dehydrogenase (SDH) stained, hematoxylin and eosin (H&E) matched transverse photomicrographs of extensor digitorum longus (EDL) at 40× magnification, b quantification of minor ellipse of oxidative SDH-stained H&E-matched myofibrils, c quantification of minor ellipse of glycolytic SDH-nonstained H&E-matched myofibrils, d proportion of oxidative (SDH-stained) myofibrils between male and female rats across 40× magnified photomicrographs (collapsed by genotype and exercise), e proportion of glycolytic (SDH-nonstained) myofibrils between HSAAR Tg and WT rats across 40× magnified photomicrographs (collapsed by sex and exercise). Photomicrographs (a) represent between-group subjects across SDH and H&E staining after the experimental paradigm. Indicated groups (b, c): males (yellow), females (green), sedentary (grey), aerobic exercise (red), wild-type (wt) (blank fill), and HSAAR transgenic (Tg) (hatch fill). Data (b, c) are presented as means ± s.e.m, with n = 6 per sex–genotype–exercise group. Data (d, e) are presented as frequency distributions. d n = 24 per sex (collapses n = 6 transgene–exercise, n = 6 wild-type–exercise, n = 6 transgene–sedentary, n = 6 wild-type–sedentary). e n = 24 per genotype (collapses n = 6 female–exercise, n = 6 male–exercise, n = 6 female–sedentary, n = 6 male–sedentary). All data analyzed using three-way ANOVA with post hoc Tukey HSD for multiple comparisons. Scale bar, 100 µmBack to article page