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Fig. 3 | Biology of Sex Differences

Fig. 3

From: miR21 deletion in osteocytes has direct and indirect effects on skeletal muscle in a sex-dimorphic manner in mice

Fig. 3

Sex-dependent alterations in kinase phosphorylation and gene expression in soleus muscles from OtmiR21Δ and miR21fl/fl mice. Multiplex protein analysis of phosphorylated and total kinase levels (N = 7–10/group) (A) and mRNA expression corrected by GAPDH levels (N = 5–6) (B) of soleus muscle lysates from female and male OtmiR21Δ and miR21fl/fl mice. Two-way ANOVA analyses were used to determine significant differences (Additional file 2: Table S2) *p < 0.05 compared to sex-matched miR21fl/fl controls, #p < 0.05 for overall male versus female comparisons, and £p < 0.05 compared to females of the same genotype

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