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Table 2 Protein expression analysis of damage-associated markers in substantia nigra and placenta

From: Gestational hypoxia in late pregnancy differentially programs subcortical brain maturation in male and female rat offspring

  

Substantia nigra

Placenta

  

Puberty

Young adult

GD20

  

Normoxia

CIH

Normoxia

CIH

Normoxia

CIH

Calpain

M

163.3 ± 28.44

180.6 ± 18.09

204.3 ± 48.88

148.4 ± 38.99

123.2 ± 21.43

115.9 ± 22.57

F

137.4 ± 31.07

165.2 ± 18.14

168.6 ± 17.66

232.2 ± 45.08

Caspase-3

M

51.68 ± 12.72

60.75 ± 13.19

75.23 ± 24.04

41.47 ± 11.15

46.68 ± 8.11

47.96 ± 13.00

F

46.55 ± 18.38

40.16 ± 9.60

70.15 ± 12.70

66.31 ± 14.90

TH

M

108.9 ± 25.36

143.0 ± 53.12

106.9 ± 40.22

154.4 ± 47.87

Not examined

F

155.4 ± 43.11

98.58 ± 32.69

69.44 ± 22.75

151.9 ± 39.41

  1. Values represent percentage of Beta Actin expression and are displayed as means ± SEM. Two-way ANOVA with Tukey’s multiple comparison test for substantia nigra comparisons (n = 5–6/group). Unpaired t test for placenta comparisons (n = 6/group). No significant differences in any comparisons (p > 0.05). GD  gestational day, CIH  chronic intermittent hypoxia, M  male, F  female, TH  tyrosine hydroxylase
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Biology of Sex Differences

ISSN: 2042-6410

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