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Table 1 Maternal parameters and reproductive outcomes of sham and RUPP (preeclampsia) groups

From: The maternal reduced uteroplacental perfusion model of preeclampsia induces sexually dimorphic metabolic responses in rat offspring

Parameter

Sham

RUPP

p-value

Maternal body weight at GD13 (before surgery)

239.5 ± 6.81

237.1 ± 7.30

0.49

Maternal body weight at GD20

308.3 ± 16.20

284.3 ± 12.39

0.001

GD13 urine protein exertion (mg/24 h)

8.25 ± 0.52

7.91 ± 0.73

0.38

GD18 urine protein exertion (mg/24 h)

8.08 ± 0.80

14.33 ± 1.50

< 0.001

GD18 blood pressure (mm/Hg)

86.66 ± 9.86

155.66 ± 11.59

0.001

GD18 heart rate (bits/minute)

241.33 ± 10.26

253.00 ± 32.07

0.58

Number of fetuses at surgery (GD14)

11.58 ± 1.16

12.8 ± 1.50

0.38

Litter size at birth

10.66 ± 1.50

11.00 ± 2.28

0.77

Number of females per litter

5.83 ± 2.22

5.66 ± 2.25

0.90

Number of males per litter

4.83 ± 1.32

5.50 ± 2.28

0.54

The mean percentage of the stillbirths

(3) 3.03%

(9) 8.71%

0.042

  1. Values are presented as mean ± SD. RUPP: reduced uteroplacental perfusion, GD13: gestational day 13, GD18: gestational day 18. Maternal data are based on 12 pregnant rats per group, except for GD18 blood pressure (n = 3)