Association of physical activity with vascular aging in a population with intermediate cardiovascular risk, analysis by sex: MARK study

Table 4 Association of physical activity with vascular aging

	Physical activity	OR	95% CI	p value
HVA (reference)
Total
M1	Total PA, (METs/m/W)	0.946	0.898 to 0.997	0.037
M2	High-intensity PA, (METs/m/W)	0.903	0.840 to 0.971	0.006
NVA	Moderate-intensity PA, (METs/m/W)	0.971	0.887 to 1.063	0.526
	Low-intensity PA, (METs/m/W)	1.079	0.928 to 1.255	0.325
M1	Total PA, (METs/m/W)	0.916	0.852 to 0.986	0.019
M2	High-intensity PA, (METs/m/W)	0.905	0.818 to 1.000	0.050
EVA	Moderate-intensity PA, (METs/m/W)	0.900	0.792 to 1.024	0.109
	Low-intensity PA, (METs/m/W)	1.035	0.852 to 1.256	0.731
Men
M1	Total PA, (METs/m/W)	0.932	0.882 to 0.986	0.013
M2	High-intensity PA, (METs/m/W)	0.898	0.832 to 0.969	0.006
NVA	Moderate-intensity PA, (METs/m/W)	0.958	0.870 to 1.054	0.377
	Low-intensity PA, (METs/m/W)	1.033	0.866 to 1.230	0.716
M1	Total PA, (METs/m/W)	0.908	0.840 to 0.982	0.016
M2	High-intensity PA, (METs/m/W)	0.896	0.804 to 0.998	0.046
EVA	Moderate-intensity PA, (METs/m/W)	0.897	0.781 to 1.029	0.835
	Low-intensity PA, (METs/m/W)	1.020	0.814 to 1.277	0.121
Women
M1	Total PA, (METs/m/W)	1.045	0.902 to 1.211	0.558
M2	High-intensity PA, (METs/m/W)	0.965	0.781 to 1.191	0.739
NVA	Moderate-intensity PA, (METs/m/W)	1.078	0.827 to 1.406	0.578
	Low-intensity PA, (METs/m/W)	1.194	0.892 to 1.597	0.233
M1	Total PA, (METs/m/W)	1.023	0.845 to 1.238	0.816
M2	High-intensity PA, (METs/m/W)	0.996	0.750 to 1.322	0.976
EVA	Moderate-intensity PA, (METs/m/W)	1.031	0.733 to 1.450	0.862
	Low-intensity PA, (METs/m/W)	1.102	0.757 to 1.603	0.614

Multinomial logistic regression analysis
Model 1. Multiple logistic regression analysis using vascular aging (HVA = 1; NVA = 2 and EVA = 3) as dependent variables (HVA reference), total physical as independent variable, as adjustment variables in the global analysis: age in years, consumption of alcohol in grams/week, years of smoking, sex (woman = 1 and man = 2), adherence to the Mediterranean diet, type 2 diabetes mellitus, arterial hypertension, obesity, antihypertensive drugs, lipid-lowering drugs and hypoglycaemic drugs (Yes = 1 and Non = 0) as adjustment variables). Model Fitting Criteria-2 Log Likelihood of Reduced Model
Model 2. Multiple logistic regression analysis using vascular aging (HVA = 1; NVA = 2 and EVA = 3) as dependent variables (HVA reference), high-intensity physical activity, moderate-intensity physical activity and low-intensity physical activity independent variable, as adjustment variables age in years, consumption of alcohol in grams/week,, years of smoking, sex (woman = 1 and man = 2), adherence to the Mediterranean diet, type 2 diabetes mellitus, arterial hypertension, obesity, antihypertensive drugs, lipid-lowering drugs and hypoglycaemic drugs (Yes = 1 and Non = 0) as adjustment variables. Model Fitting Criteria -2 Log Likelihood of Reduced Model
M1, Model 1: M2, Model 2; HVA, healthy vascular aging; NVA, normal vascular aging; EVA, early vascular aging; PA, physical activity; METs/m/W, metabolic equivalents/min/week

ISSN: 2042-6410