Skip to main content
Fig. 3 | Biology of Sex Differences

Fig. 3

From: Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition

Fig. 3

Effect of EMPA on mRNA expression on antioxidant enzymes in white adipose depots in PCOS. Effect of EMPA on subcutaneous white adipose tissue (WAT) mRNA expression of A cytosolic superoxide dismutase (SOD1), B mitochondrial superoxide dismutase (SOD2), and C catalase; retroperitoneal WAT mRNA expression of D SOD1, E SOD2, and F catalase; and mesenteric WAT mRNA expression of G SOD1, H SOD2, and I catalase after 3 weeks of EMPA treatment. Expression was normalized by the geometric mean of three housekeeping genes (GMHK) and standardized to untreated control rats. Log2 values are expressed as mean ± SEM. Data were analyzed by two-way ANOVA followed by Tukey post hoc tests. Significant interactions were observed for SOD1, SOD2, and catalase in subcutaneous WAT, in SOD2 in retroperitoneal WAT, and in SOD1 in mesenteric WAT. *P < 0.05. n = 7–8 per group

Back to article page

Biology of Sex Differences

ISSN: 2042-6410

Contact us