Table 2 Statistical tests for independent sample analyses
From: Nk3R blockade has sex-divergent effects on memory in mice
Between-subjects variables | Snedecor’s F | p-value | |
|---|---|---|---|
df | Value | ||
Preference test | |||
Sex | 1,24 | 0.057 | 0.813 |
Object | 1,24 | 0.072 | 0.791 |
Sex × Object | 1,24 | 0.072 | 0.791 |
Familiarization (5 mg/kg) | |||
Sex | 1,56 | 0.000 | 1.000 |
Object | 1,56 | 0.031 | 0.860 |
Treatment | 1,56 | 0.000 | 1.000 |
Sex × Object | 1,56 | 0.359 | 0.552 |
Sex × Treatment | 1,56 | 0.000 | 1.000 |
Object × Treatment | 1,56 | 1.128 | 0.293 |
Sex × Object × Treatment | 1,56 | 0.006 | 0.939 |
NOR test (5 mg/kg) | |||
Sex | 1,28 | 1.748 | 0.197 |
Treatment | 1,28 | 0.227 | 0.603 |
Sex × Treatment | 1,28 | 0.002 | 0.965 |
Familiarization (10 mg/kg) | |||
Sex | 1,5 | 0.000 | 1.000 |
Object | 1,5 | 0.000 | 1.000 |
Treatment | 1,5 | 0.103 | 0.749 |
Sex × Object | 1,5 | 0.091 | 0.764 |
Sex × Treatment | 1,5 | 0.000 | 1.000 |
Object × Treatment | 1,5 | 1.638 | 0.206 |
Sex × Object × Treatment | 1,5 | 2.651 | 0.110 |
NOR test (10 mg/kg) | |||
Sex | 1,25 | 10.595 | 0.003 |
Treatment | 1,25 | 0.022 | 0.884 |
Sex × Treatment | 1,25 | 17.128 | 0.000 |
Treatment in males | 1,25 | 9.496 | 0.005 |
Treatment in females | 1,25 | 7.714 | 0.010 |
Nk3R expression | |||
Sex | 1,43 | 7.770 | 0.008 |
Area | 5,44 | 1.631 | 0.257 |
Sex × Area | 5,44 | 0.768 | 0.758 |
ERα expression | |||
Sex | 1,47 | 7.001 | 0.011 |
Area | 5,47 | 1.789 | 0.133 |
Sex × Area | 5,47 | 1.326 | 0.270 |
ERβ expression | |||
Sex | 1,41 | 115.275 | 0.000 |
Area | 5,41 | 28.389 | 0.000 |
Sex × Area | 5,41 | 26.475 | 0.000 |
Sex in CA1 | 1,41 | 21.410 | 0.000 |
Sex in CA3 | 1,41 | 0.001 | 0.973 |
Sex in DG | 1,41 | 98.405 | 0.000 |
Sex in CG | 1,41 | 105.908 | 0.000 |
Sex in IL | 1,41 | 0.000 | 0.985 |
Sex in PrL | 1,41 | 0.029 | 0.866 |
AR expression | |||
Sex | 1,42 | 1.388 | 0.245 |
Area | 5,42 | 9.144 | 0.000 |
Sex × Area | 5,42 | 0.475 | 0.793 |
CG vs rest of areas | Bonferroni correction | 0.000 | |
Nk3R–GPAR positive cells | |||
Sex | 1,60 | 8.402 | 0.005 |
Area | 5,60 | 0.688 | 0.635 |
Sex × Area | 5,60 | 0.717 | 0.613 |
Nk3R–GPER positive cells | |||
Sex | 1,60 | 290.103 | 0.000 |
Area | 5,60 | 1.609 | 0.171 |
Sex × Area | 5,60 | 3.810 | 0.005 |
Sex in CA1 | 1,10 | 0.001 | 0.972 |
Sex in CA3 | 1,10 | 0.274 | 0.612 |
Sex in DG | 1,10 | 2.906 | 0.119 |
Sex in CG | 1,10 | 3.929 | 0.076 |
Sex in IL | 1,10 | 3.929 | 0.076 |
Sex in PrL | 1,10 | 5.033 | 0.049 |