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Table 2 Statistical tests for independent sample analyses

From: Nk3R blockade has sex-divergent effects on memory in mice

Between-subjects variables Snedecor’s F p-value
df Value
Preference test
 Sex 1,24 0.057 0.813
 Object 1,24 0.072 0.791
 Sex × Object 1,24 0.072 0.791
Familiarization (5 mg/kg)
 Sex 1,56 0.000 1.000
 Object 1,56 0.031 0.860
 Treatment 1,56 0.000 1.000
 Sex × Object 1,56 0.359 0.552
 Sex × Treatment 1,56 0.000 1.000
 Object × Treatment 1,56 1.128 0.293
 Sex × Object × Treatment 1,56 0.006 0.939
NOR test (5 mg/kg)
 Sex 1,28 1.748 0.197
 Treatment 1,28 0.227 0.603
 Sex × Treatment 1,28 0.002 0.965
Familiarization (10 mg/kg)
 Sex 1,5 0.000 1.000
 Object 1,5 0.000 1.000
 Treatment 1,5 0.103 0.749
 Sex × Object 1,5 0.091 0.764
 Sex × Treatment 1,5 0.000 1.000
 Object × Treatment 1,5 1.638 0.206
 Sex × Object × Treatment 1,5 2.651 0.110
NOR test (10 mg/kg)
 Sex 1,25 10.595 0.003
 Treatment 1,25 0.022 0.884
 Sex × Treatment 1,25 17.128 0.000
 Treatment in males 1,25 9.496 0.005
 Treatment in females 1,25 7.714 0.010
Nk3R expression
 Sex 1,43 7.770 0.008
 Area 5,44 1.631 0.257
 Sex × Area 5,44 0.768 0.758
ERα expression
 Sex 1,47 7.001 0.011
 Area 5,47 1.789 0.133
 Sex × Area 5,47 1.326 0.270
ERβ expression
 Sex 1,41 115.275 0.000
 Area 5,41 28.389 0.000
 Sex × Area 5,41 26.475 0.000
 Sex in CA1 1,41 21.410 0.000
 Sex in CA3 1,41 0.001 0.973
 Sex in DG 1,41 98.405 0.000
 Sex in CG 1,41 105.908 0.000
 Sex in IL 1,41 0.000 0.985
 Sex in PrL 1,41 0.029 0.866
AR expression
 Sex 1,42 1.388 0.245
 Area 5,42 9.144 0.000
 Sex × Area 5,42 0.475 0.793
 CG vs rest of areas Bonferroni correction 0.000
Nk3R–GPAR positive cells
 Sex 1,60 8.402 0.005
 Area 5,60 0.688 0.635
 Sex × Area 5,60 0.717 0.613
Nk3R–GPER positive cells
 Sex 1,60 290.103 0.000
 Area 5,60 1.609 0.171
 Sex × Area 5,60 3.810 0.005
 Sex in CA1 1,10 0.001 0.972
 Sex in CA3 1,10 0.274 0.612
 Sex in DG 1,10 2.906 0.119
 Sex in CG 1,10 3.929 0.076
 Sex in IL 1,10 3.929 0.076
 Sex in PrL 1,10 5.033 0.049
  1. Two or three-way ANOVAs were performed to assess statistical significance for independent sample analyses. Significant main effects and interactions between main effects are indicated in italic. Bonferroni post hoc analysis was used to assess significance between categories of a significant multiple-category main effect