Increased basal insulin sensitivity in late pregnancy in women carrying a male fetus: a cohort study

Table 3 Selected OGTT assessment of the glucose-insulin axis, including surrogate indices of insulin secretion

Variable	n	Unadjusted		Adjusted*
Variable	n	β′	p	β′	p
HOMA B	813	− 0.035 (− 0.103, 0.034)	0.3	− 0.033 (− 0.095, 0.030)	0.3
OGTT 60-min. insulin concentration	805	0.036 (− 0.032, 0.104)	0.3	0.022 (− 0.040, 0.083)	0.5
OGTT 60-min. glucose concentration	806	0.014 (− 0.042, 0.071)	0.6	− 0.008 (− 0.057, 0.040)	0.7
OGTT 120-min. capillary glucose concentration	610	− 0.037 (− 0.118, 0.043)	0.4	− 0.052 (− 0.125, 0.020)	0.2
0–60-min. insulin increment	805	0.038 (− 0.029, 0.106)	0.3	0.026 (− 0.037, 0.088)	0.4
0–60-min. insulinogenic index	768	0.031 (− 0.037, 0.099)	0.4	0.040 (− 0.027, 0.108)	0.2
0–60-min. insulin disposition index	768	0.066 (− 0.005, 0.136)	0.07	0.090 (0.025, 0.156)	0.007

Where significant associations have positive standardised β′s, values from women carrying male fetuses are higher than those from women carrying females. Where significant associations have negative standardised β′s, values from women carrying female fetuses are higher than those from women carrying males
*Adjusted for pre-pregnancy BMI, maternal age, gestational age of fetus, multi-fetal pregnancy and GDM

ISSN: 2042-6410