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Fig. 6 | Biology of Sex Differences

Fig. 6

From: Neurogenesis in the neonatal rat hippocampus is regulated by sexually dimorphic epigenetic modifiers

Fig. 6

Treatment with ZEB decreases proliferation in the newborn male DG, while TSA treatment increases proliferation in female DG. A Treatment with ZEB and TSA within the same cohort, to eliminate potential liter effects or other bias, confirmed that ZEB administration decreases proliferation in the male DG and TSA administration increases proliferation in the female DG (***p < 0.001, sex difference in proliferation; **p < 0.001, effect of ZEB treatment in males; *p < 0.05, effect of TSA treatment in females). B Representative images of BrdU labeling in the DG of male rats treated with ZEB or vehicle and female rats treated with TSA or vehicle on PN0 and PN1

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