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Fig. 3 | Biology of Sex Differences

Fig. 3

From: Neurogenesis in the neonatal rat hippocampus is regulated by sexually dimorphic epigenetic modifiers

Fig. 3

HDAC inhibitor TSA increases proliferation in the DG of females only. A, B Administration of 0.5 mg/Kg of TSA, significantly increased H3K9/14 and H4 acetylation in the DG of newborn males and females (main effect of treatment, *p < 0.05, ****p < 0.0001). C Treatment of TSA interacted with sex to affect proliferation in the DG as TSA treatment increased proliferation only in the female DG (significant interaction, *p < 0.05, **p < 0.01, compared to vehicle-treated females)

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