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Table 2 Clinical characteristics of study patients according to the presence of obstructive CAD and sex

From: Sex differences in coronary angiographic findings in patients with stable chest pain: analysis of data from the KoRean wOmen’S chest pain rEgistry (KoROSE)

Characteristic

Men (n = 941)

Women (n = 1407)

Obstructive CAD (−)

(n = 517)

Obstructive CAD (+)

(n = 424)

P value

Obstructive CAD (−)

(n = 907)

Obstructive CAD (+)

(n = 500)

P value

Age, years

57.0 ± 11.6

62.6 ± 10.2

 < 0.001

62.4 ± 10.3

68.1 ± 9.1

 < 0.001

BMI, kg/m2

25.0 ± 3.1

25.2 ± 3.1

0.536

25.1 ± 3.7

25.0 ± 3.7

0.389

Waist circumference, cm

86.0 ± 9.0

87.6 ± 10.1

0.082

82.0 ± 10.1

83.9 ± 9.6

0.016

Systolic blood pressure, mmHg

126 ± 16

130 ± 18

0.005

124 ± 17

130 ± 20

 < 0.001

Diastolic blood pressure, mmHg

79.7 ± 11.5

78.2 ± 11.7

0.088

75.1 ± 11.3

76.1 ± 12.2

0.188

Heart rate, per minute

75.1 ± 13.9

74.3 ± 13.2

0.426

74.2 ± 12.2

74.9 ± 13.5

0.418

Cardiovascular risk factors, %

      

 Hypertension

47.4

61.1

 < 0.001

49.3

67.7

 < 0.001

 Diabetes mellitus

19.6

36.2

 < 0.001

17.8

34.6

 < 0.001

 Dyslipidemia

26.0

24.5

0.653

27.3

25.6

0.526

 Current smoking

31.5

39.1

0.021

4.9

4.8

0.972

 Obesity (BMI ≥ 25 kg/m2)

51.1

52.0

0.807

46.0

46.4

0.889

Laboratory findings

      

 WBC, per microliter

6764 ± 2118

7175 ± 2098

0.005

6471 ± 2237

7405 ± 3156

 < 0.001

 Hemoglobin, g/dL

14.5 ± 1.5

14.0 ± 1.6

 < 0.001

12.9 ± 1.3

12.5 ± 1.6

 < 0.001

 GFR, mL/min/1.73 m2

82.1 ± 19.4

80.8 ± 23.4

0.356

84.1 ± 27.5

81.9 ± 31.6

0.204

 Fasting glucose, mg/dL

113 ± 36

127 ± 52

 < 0.001

112 ± 40

129 ± 53

 < 0.001

 Glycated hemoglobin, %

5.97 ± 1.05

6.58 ± 1.38

 < 0.001

6.04 ± 0.99

6.39 ± 1.26

 < 0.001

 Total cholesterol, mg/dL

165 ± 40

162 ± 43

0.218

171 ± 43

173 ± 46

0.491

 LDL cholesterol, mg/dL

102 ± 34

100 ± 38

0.435

101 ± 35

107 ± 37

0.018

 HDL cholesterol, mg/dL

45.2 ± 12.2

41.6 ± 10.6

 < 0.001

51.1 ± 13.9

45.8 ± 11.1

 < 0.001

 Triglyceride, mg/dL

155 ± 108

152 ± 116

0.776

123 ± 75

133 ± 105

0.079

 C-reactive protein, mg/dL

2.74 ± 11.5

1.39 ± 3.56

0.101

0.79 ± 2.47

1.28 ± 4.22

0.081

Concomitant medications, %

      

 Antiplatelet

36.9

63.8

 < 0.001

43.1

65.9

 < 0.001

 Calcium channel blocker

29.1

39.6

0.002

33.5

34.9

0.632

 Beta-blocker

15.9

32.3

 < 0.001

23.5

39.8

 < 0.001

 RAS blocker

33.0

47.3

 < 0.001

34.5

49.0

 < 0.001

 Statin

42.6

62.7

 < 0.001

52.4

64.3

 < 0.001

  1. CAD coronary artery disease; BMI body mass index; WBC white blood cell; GFR glomerular filtration rate; LDL low-density lipoprotein; HDL high-density lipoprotein; RAS renin–angiotensin system
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Biology of Sex Differences

ISSN: 2042-6410

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