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Table 4 Hemodynamic, cardiac and pulmonary variables at a fixed submaximal workload (100 W)

From: Sex and age interaction in fundamental circulatory volumetric variables at peak working capacity

 

Young

Older

P for age comparison

P for sex

P for sex

Submaximal hemodynamics

 SBP100W (mm Hg)

159.0 ± 21.2

157.2 ± 34.3

0.878

218.6 ± 48.9a

205.3 ± 39.5a

0.318

 < 0.001

 < 0.001

 DBP100W (mm Hg)

96.6 ± 27.3

90.5 ± 19.5

0.536

111.4 ± 24.9

103.5 ± 21.1

0.257

0.124

0.084

 MBP100W (mm Hg)

107.4 ± 13.8

109.5 ± 23.0

0.791

143.2 ± 31.3a

135.0 ± 24.9a

0.337

 < 0.001

0.006

 SVR100W (dyn s cm−5)

1137.7 ± 246.7

1011.6 ± 310.1

0.283

1923.5 ± 712.6a

1573.8 ± 591.5a

0.079

 < 0.001

0.004

 HR100W (bpm)

123.5 ± 20.1

105.6 ± 14.9*

0.013

121.0 ± 15.0

102.2 ± 11.3*

 < 0.001

0.655

0.415

Submaximal echocardiography

 RA100W (mL m−2)

16.10 ± 7.50

16.74 ± 5.56

0.801

13.41 ± 3.92

17.49 ± 6.01*

0.005

0.137

0.701

 RV EDA100W (cm2 m−2)

10.05 ± 2.77

11.17 ± 1.98

0.233

9.07 ± 2.05

10.72 ± 1.67*

0.002

0.207

0.451

 RV ESA100W (cm2 m−2)

4.42 ± 1.40

4.47 ± 0.89

0.910

3.77 ± 1.10

4.06 ± 1.20

0.345

0.108

0.266

 LA100W (mL m−2)

15.07 ± 7.40

15.53 ± 7.18

0.870

17.09 ± 6.23

19.98 ± 7.89

0.142

0.362

0.085

 LVEDV100W (mL m−2)

46.16 ± 7.91

56.43 ± 9.32*

0.004

43.03 ± 8.87

49.87 ± 15.19*

0.049

0.274

0.149

 LVESV100W (mL m−2)

10.22 ± 2.39

13.51 ± 2.98*

0.003

10.05 ± 3.99

12.48 ± 6.64

0.108

0.882

0.586

 LVEF100W (%)

77.9 ± 3.4

75.8 ± 5.2

0.229

77.1 ± 6.1

75.6 ± 8.8

0.466

0.662

0.918

 SV100W (mL m−2)

35.90 ± 6.41

42.91 ± 8.36*

0.019

32.98 ± 6.61

37.39 ± 11.62

0.093

0.185

0.123

 Q100W (L min−1 m−2)

4.37 ± 0.70

4.51 ± 0.92

0.656

3.95 ± 0.73

3.85 ± 1.37

0.724

0.082

0.109

Submaximal pulmonary variables

 VO2,100 W (mL min−1)

1395.1 ± 331.7

1349.4 ± 359.0

0.760

1314.7 ± 355.8

1376.2 ± 367.1

0.535

0.524

0.838

 VO2,100 W (mL min−1 kg−1)

21.4 ± 4.5

17.1 ± 4.0*

0.028

22.2 ± 6.2

17.5 ± 5.1*

0.003

0.695

0.837

 Ve100W (L min−1)

21.9 ± 9.0

20.6 ± 15.1

0.801

33.0 ± 15.4a

28.8 ± 13.9

0.293

0.033

0.117

  1. Significant P values (< 0.05) are highlighted in bold
  2. Data are expressed as mean ± SD
  3. DBP100W, submaximal (100 W) diastolic blood pressure; HR100W, submaximal (100 W) heart rate; LA100W, submaximal (100 W) left atria; LVEDV100W, submaximal (100 W) left ventricular end-diastolic volume; LVEF100W, submaximal (100 W) left ventricular ejection fraction; MBP100W, submaximal (100 W) mean blood pressure; Q100W, submaximal (100 W) cardiac output; RA100W, submaximal (100 W) right atria; RV EDA100W, submaximal (100 W) right ventricular end-diastolic area; RV ESA100W, submaximal (100 W) right ventricular end-systolic area; SBP100W, submaximal (100 W) systolic blood pressure; SV100W, submaximal (100 W) stroke volume: SVR100W, submaximal (100 W) systemic vascular resistance; Ve100W, submaximal (100 W) ventilation; VO2,100W, submaximal (100 W) oxygen uptake
  4. *P < 0.05 compared with age-matched women
  5. aP < 0.05 compared with sex-matched young individuals