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Table 2 Multivariable linear regression models to assess independent relationships of P/F (in mmHg), age and the other biomarkers as predictors in women and men with COVID-19

From: Predicting respiratory failure in patients infected by SARS-CoV-2 by admission sex-specific biomarkers

Predictors Dependent variable: P/F (mm Hg)
Women Men
Adjusted coefficient 95% Conf. Int P Adjusted coefficient 95% Conf. Int P
Age class (≤ 45 vs 55 ≥) − 72.061 − 131.901 − 12.221 0.019 − 56.563 − 116.151 3.024 0.062
Number of lymphocytes in the lowest count (n. cells/L) 0.451 0.097 0.805 0.014 0.242 − 0.169 0.653 0.243
Number of neutrophils in the highest count (n. cells/L) − 8.575 − 12.806 − 4.344  < 0.001 − 4.222 − 6.693 − 1.751 0.001
Ferritin concentration (ng/mL) − 0.032 − 0.060 − 0.005 0.020 − 0.069 − 0.113 − 0.025 0.003
17β-estradiol concentration (pg/mL) 0.766 0.017 1.514 0.045 − 1.098 − 2.756 0.561 0.191
Testosterone concentration (ng/mL) − 0.371 − 2.243 1.500 0.692 1.385 0.002 2.767 0.050
Comorbidities       
 No comorbidities 1 (ref.)    1 (ref.)   
 One comorbidity − 21.540 − 81.161 38.081 0.472 − 44.305 − 94.975 6.366 0.085
 Two or more comorbidities − 35.351 − 105.264 34.561 0.316 − 66.145 − 125.909 − 6.381 0.031