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Table 2 Multivariable linear regression models to assess independent relationships of P/F (in mmHg), age and the other biomarkers as predictors in women and men with COVID-19

From: Predicting respiratory failure in patients infected by SARS-CoV-2 by admission sex-specific biomarkers

Predictors

Dependent variable: P/F (mm Hg)

Women

Men

Adjusted coefficient

95% Conf. Int

P

Adjusted coefficient

95% Conf. Int

P

Age class (≤ 45 vs 55 ≥)

− 72.061

− 131.901

− 12.221

0.019

− 56.563

− 116.151

3.024

0.062

Number of lymphocytes in the lowest count (n. cells/L)

0.451

0.097

0.805

0.014

0.242

− 0.169

0.653

0.243

Number of neutrophils in the highest count (n. cells/L)

− 8.575

− 12.806

− 4.344

 < 0.001

− 4.222

− 6.693

− 1.751

0.001

Ferritin concentration (ng/mL)

− 0.032

− 0.060

− 0.005

0.020

− 0.069

− 0.113

− 0.025

0.003

17β-estradiol concentration (pg/mL)

0.766

0.017

1.514

0.045

− 1.098

− 2.756

0.561

0.191

Testosterone concentration (ng/mL)

− 0.371

− 2.243

1.500

0.692

1.385

0.002

2.767

0.050

Comorbidities

      

 No comorbidities

1 (ref.)

  

1 (ref.)

  

 One comorbidity

− 21.540

− 81.161

38.081

0.472

− 44.305

− 94.975

6.366

0.085

 Two or more comorbidities

− 35.351

− 105.264

34.561

0.316

− 66.145

− 125.909

− 6.381

0.031