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Fig. 2 | Biology of Sex Differences

Fig. 2

From: Sexually dimorphic patterns in maternal circulating microRNAs in pregnancies complicated by fetal growth restriction

Fig. 2

Interacting mRNA networks of all altered miRNAs. A, B A list of all 11 miRNAs altered in FGR was uploaded to miRNET and A networks of interacting genes (pink circles) associated with altered miRNAs (blue square) were determined. B Functional enrichment analysis of network genes was performed using Reactome, GO and KEGG. Key functional effects associated with the network were found in pathways associated with cellular response to stress (red; 77 node genes; Adj p = 4.9 × 10–6), cell proliferation (yellow; 111 node genes; Adj p value = 0.00012) and vascular development (turquoise; 97 node genes; Adj p value = 0.00037)

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Biology of Sex Differences

ISSN: 2042-6410

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