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Table 2 GDF-15 linear regression analysis in males

From: Role of GDF-15, YKL-40 and MMP 9 in patients with end-stage kidney disease: focus on sex-specific associations with vascular outcomes and all-cause mortality

  Estimate Standard error p-value
Vascular calcification
 Model 1
  lnCAC score 0.285 0.131 0.034
 Model 2
  lnCAC score 0.286 0.125 0.026
Inflammatory biomarkers
 Model 1
  IL-6 0.199 0.076 0.011
  hsCRP − 0.020 0.061 0.747
  TNF-alfa − 0.029 0.044 0.504
 Model 2
  IL-6 0.167 0.080 0.040
  hsCRP − 0.028 0.061 0.654
  TNF-alfa − 0.019 0.044 0.675
  1. Bold signifies statistical significance p < 0.05
  2. Model 1: adjusted for age, cardiovascular disease, diabetes mellitus, kidney function
  3. Model 2: Model 1 + adjusted for mortality
  4. lnCAC logarithmic coronary artery calcification, expressed as ln(CAC + 1), hsCRP high sensitivity C-reactive protein, IL-6 interleukin 6, TNF tumour necrosis factor