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Fig. 4 | Biology of Sex Differences

Fig. 4

From: Activation of G protein-coupled estradiol receptor 1 in the dorsolateral striatum enhances motivation for cocaine and drug-induced reinstatement in female but not male rats

Fig. 4

There are sex differences in the effects of GPER1 activation on motivation for cocaine. During weeks 3 and 4 of progressive ratio (PR), G1-treated females have significantly greater breaking point than they did during weeks 1 and 2, prior to treatment (p < 0.0001). G1-treated females also have a greater breaking point than G1-treated males, during weeks 3 and 4 of PR (p = 0.0039). Data are presented as mean ± SEM

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Biology of Sex Differences

ISSN: 2042-6410

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