From: Testosterone and depressive symptoms during the late menopause transition
| Baseline characteristics | |
|---|---|
| Age, mean (SD) | 49.8 (2.6) |
| Years of education, mean (SD) | 13.2 (5.8) |
| Education level, (%) | |
| High school diploma | 22% |
| Some university | 33% |
| Undergraduate degree | 29% |
| Graduate degree | 16% |
| Family income, mean (SD), 10K | |
| < $70,000 | 17% |
| $70,000–89,999 | 19% |
| $90,000–112,999 | 15% |
| ≥ $113,000 | 43% |
| No response | 6% |
| Ethnicity, (%) | |
| Caucasian | 86% |
| Black | 2% |
| Hispanic | 4% |
| Others | 8% |
| Months since LMP, mean (SD) | 2.2 (1.7) |
| Baseline STRAW status (%) | |
| Early perimenopause | 34% |
| Late perimenopause | 66% |
| STRAW status at the end of phase 1 (%) | |
| Early perimenopause | 8% |
| Late perimenopause | 84% |
| Early postmenopause | 5% |
| Body mass index (BMI; kg/m2) | 29.4 (6.5) |
| Overweight (25 ≤ BMI < 29.9 kg/m2) | 38% |
| Obese (BMI ≥ 30 kg/m2) | 36% |
| Smoking status (%) | |
| Never smokers | 57% |
| Past smokers | 34% |
| Current smokers | 10% |
| History of major depression (%) | 38% |
| Weekly variables | |
| CES-D score, mean (SD) | 12.0 (8.0) |
| Number of hot flashes, mean (SD) | |
| Mild | 1.9 (1.1) |
| Moderate | 1.7 (1.0) |
| Severe | 1.4 (1.0) |
| Sleep quality score, mean (SD) | 2.3 (0.9) |
| E1G, mean (SD), pg/ml | 39,624 (19,809) |
| Testosterone, mean (SD), pg/ml | 2113 (1295) |
| Testosterone-to-E1G ratio, mean (SD) | 0.068 (0.055) |