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Fig. 4 | Biology of Sex Differences

Fig. 4

From: Sexual dimorphism of monocyte transcriptome in individuals with chronic low-grade inflammation

Fig. 4

Violin plot of female/male fold change (log2) distribution of the genes in C1–C5 clusters of the IFN regulatory network constructed by Mostafavi et al. from peripheral blood monocytes. Each cluster denotes distinct function: C1-2 [RNA processing], C3 [antiviral effectors], C4 [metabolic regulation], and C5 [inflammation mediators or regulators]. The central line of each cluster indicates the median, and the bottom and top lines indicate the 25th and 75th percentiles, respectively. The clusters having mean fold changes significantly different from zero (one sample two-sided t test with Bonferroni correction) are marked with graded asterisks. * Adjusted p < 0.05; *** Adjusted p < 0.001

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