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Table 4 Overlap of placental autosomal differentially methylated CpGs reported in this study with previous literature

From: A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta

Study Martin et al. 2017 Mayne et al. 2017
Sample size (n, % female) 84 (69%) 62 (56%)
Gestational age (mean weeks) 25.5 ≥ 37
Autosomal DMPs reported (n) 21 420
Autosomal DMPs with higher male β (%) 62% 100%
Autosomal DMP probes covered in this study (n)* 0/21 335/420
Overlap with present study
 FDR < 0.05, Δβ > 0.10 (n = 162) - 0/335
 FDR < 0.05, no Δβ (n = 24,715) - 84/335
 Genes at FDR < 0.05 (n = 6,733) - 154/335
  1. *Due to differences in probe filtering, not all DMPs reported in previous studies were in the filtered dataset of 324,104 autosomal CpGs used here, overlap only considered for common CpGs