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Table 4 Overlap of placental autosomal differentially methylated CpGs reported in this study with previous literature

From: A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta

Study

Martin et al. 2017

Mayne et al. 2017

Sample size (n, % female)

84 (69%)

62 (56%)

Gestational age (mean weeks)

25.5

≥ 37

Autosomal DMPs reported (n)

21

420

Autosomal DMPs with higher male β (%)

62%

100%

Autosomal DMP probes covered in this study (n)*

0/21

335/420

Overlap with present study

 FDR < 0.05, Δβ > 0.10 (n = 162)

-

0/335

 FDR < 0.05, no Δβ (n = 24,715)

-

84/335

 Genes at FDR < 0.05 (n = 6,733)

-

154/335

  1. *Due to differences in probe filtering, not all DMPs reported in previous studies were in the filtered dataset of 324,104 autosomal CpGs used here, overlap only considered for common CpGs