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Table 2 Maternal cardiac data in reduced uterine perfusion pressure rat model

From: Characterisation of cardiac health in the reduced uterine perfusion pressure model and a 3D cardiac spheroid model, of preeclampsia

  Sham (n ≥ 6) RUPP (n ≥ 4) p value
Maternal body weight (before surgery), g 338.6 ± 17.5 379.5 ± 4.87 0.084
Maternal heart weight, g 1.02 ± 0.05 1.22 ± 0.01 0.008**
Heart: Body weight, % 0.304 ± 0.01 0.323 ± 0.005 0.303
Embryo resorption (%) 2.38 ± 1.51 11.22 ± 3.06 0.04*
Embryo weight, g 1.68 ± 0.025 1.61 ± 0.02 0.04
Placental weight, g 0.41 ± 0.009 0.39 ± 0.006 0.047
Heart rate, bpm 369.3 ± 4.8 398.8 ± 3.7 0.0006***
Systolic BP, mmHg 112.6 ± 1.3 127.8 ± 1.9 < 0.0001***
Diastolic BP, mmHg 87.6 ± 1.7 104.0 ± 1.8 < 0.0001***
MABP, mmHg 100.9 ± 1.5 116.7 ± 1.7 < 0.0001***
Stroke volume, μl 215.0 ± 4.326 230.0 ± 13.26 0.304
Cardiac output, mL/min 79 ± 3 85 ± 5 0.067
Ejection fraction, % 82 ± 2 78 ± 2 0.233
Fractional shortening, % 52 ± 2 49 ± 2 0.236
Corrected LV mass, mg 600 ± 14 706 ± 68 0.037*
LV anterior wall systolic, mm 2.9 ± 0.12 2.9 ± 0.11 0.672
LV anterior wall diastolic, mm 1.5 ± 0.04 1.8 ± 0.17 0.152
LV posterior wall systolic, mm 2.8 ± 0.14 2.9 ± 0.09 0.303
LV posterior wall diastolic, mm 1.6 ± 0.05 1.6 ± 0.11 0.994
  1. BP, blood pressure; LV, left ventricular, MABP, mean arterial blood pressure; RUPP, reduced uterine perfusion pressure
  2. Unpaired Student’s t-test or Mann-Whitney test depending on data distribution; *p < 0.05, ***p < 0.001