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Table 4 Multiple regression analysis with eGFR

From: Sex differences in soluble prorenin receptor in patients with type 2 diabetes

Predictors Urine Renin Activity Plasma sPRR Urine sPRR
β t P value β t P value β t P value
Model 1—constant 94.47 49.29 < 0.001 100.52 20.55 < 0.001 86.11 41.58 < 0.001
Model 2—constant 114.89 9.61 < 0.001 117.29 10.18 < 0.001 112.37 9.88 < 0.001
Type 2 diabetes − 3.79 − 0.89 0.377 − 5.19 − 1.39 0.1673 − 2.76 − 0.74 0.462
Age − 0.70 − 5.75 < 0.001 − 0.72 − 6.25 < 0.001 − 0.688 − 5.51 < 0.001
Sex 3.09 1.02 0.307 3.81 1.40 0.1640 3.73 1.31 0.190
Race − 9.66 − 3.05 0.0026 − 11.67 − 4.01 < 0.001 − 11.89 − 4.01 < 0.001
Body weight (kg) − 0.06 − 0.18 0.010 − 0.486 − 1.83 0.073 2.69 2.52 0.012
BMI 0.33 1.68 0.093 0.197 1.08 0.2829 0.17 0.92 0.359
DBP 0.137 0.90 0.371 0.154 1.06 0.2887 0.22 1.42 0.158
SBP − 0.05 − 0.53 0.594 − 0.04 − 0.40 0.6877 − 0.09 − 0.92 0.359
Anti-hypertensives − 1.18 − 1.96 0.052 − 1.751 − 3.254 0.001 − 2.10 − 3.94 < 0.001
Anti-diabetic medications 1.84 0.29 0.773 3.762 0.639 0.524 0.85 6.11 0.900
  1. Urine Renin Activity: Model 1: P = 0.0038, R2 = 3.9%; Model 2: P < 0.001, R2 = 24.32%
  2. Plasma sPRR: Model 1: P = 0.0058, R2 = 3.4%; Model 2: P < 0.001, R2 = 25.67%
  3. Urine sPRR Model 1: P = 0.0357, R2 = 3.4%; Model 2: P = 0.001, R2 = 26.61%