Table 2 Soluble PRR, renin, prorenin, AGT, and TGF-β1 in plasma and urine

 sPRR (ng/mL)

16.5 (15.8–17)

19.2 (17–21)^*

0.001

18 (16.5–19)

17 (16–20)

0.87

15 (14.8–16) †

20 (18–22)‡

^†0.05

^‡0.001

 Renin activity (ng Ang-I /mL/h)

3.2 (2.7–3.8)

12 (10–14)^*

0.001

3.5 (2.5–4.5)

9.8 (6.4–13.3)^{† ‡ **}

^†0.001

^‡0.001

^**0.05

3.0 (2.3–3.7)

13 (11–15.6)^† ‡

^†0.001

^‡0.001

 sPRR/uCr (ng/mg)

1.6 (1.3–1.8)

0.8 (0.6–1)^*

0.001

1.8 (1.4–2.4)

0.6 (0.4–0.8)^† ‡

^†0.001

^‡0.05

1.3 (1–1.7)

1.0 (0.75–1.3) †

^†0.001

 Renin activity (ng Ang-I /mL/h)

27 (21–33)

99 (77–120)^*

0.001

27 (16.5–37.4)

125 (82–168)^{† ‡ **}

^†0.001

^‡0.001

^**0.05

27 (20–34)

84 (60–108)^† ‡

^†0.001

^‡0.001

 Prorenin/uCr (ng/g)

141 (109–173)

302 (232–371)^*

0.01

128 (91–165)

362 (215–508)^† ‡

^†0.01

^‡0.05

153 (103–204)

273 (199–348)^†

^†0.01

 AGT/uCr (μg/g)

16 (13–19)

25 (17–32)^*

0.02

15 (11–20)

30 (17–42)^† ‡

^†0.05

^‡0.05

16 (12–20)

21 (11–20)

0.52

 TGF-β1/uCr (pg/mg)

18 (14–22)

31 (24–38)^*

0.001

16 (11–21)

33 (20–45)^†

^†0.05

19 (13–25)

31 (23–39)^†

^†0.05