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Table 1 Demographic, clinical characteristics, demographic, and medications

From: Sex differences in soluble prorenin receptor in patients with type 2 diabetes

Variables

Total participants

Men

Women

Control

Type 2 diabetes

Control

Type 2 diabetes

Control

Type 2 diabetes

Participants, n (%)

173 (64)

96 (36)

71 (63)

41 (37)

102 (65)

55 (35)

Age

39 (13)

55 (9)

40 (13)

56 (8)

39 (13)

55 (10)

Caucasians, n (%)

114 (42)

44 (16)

44 (16)

19 (7)

70 (26)

25 (9)

African American, n (%)

59 (22)

52 (20)

27 (55)

22 (45)

32 (51)

30 (49)

Clinical analysis

      

 BMI (kg/m2)

28 (7.9)

37.5 (7.4)

28 (6.9)

38 (7)

28 (8.6)

37 (7.8)

 WHR

0.8 (0.1)

0.9 (0.1)

0.91 (0.08)

1.0 (0.05)

0.81 (0.07)

0.89 (0.1)

 SBP (mm Hg)

118 (15)

132 (22)

121(14)

133 (25)

116 (15)

131 (20)

 DBP (mm Hg)

74 (11)

80 (12)

74 (12)

80 (14)

73 (12)

80 (12)

 Fasting glucose (mg/dL)

77 (19)

134 (54)

82 (18)

150 (54)

75 (19)

122 (51)

 HbA1C (%)

–

7.6 (1.7)

–

8.3 (2)

–

7.2 (1)

 Serum creatinine (mg/dL)

0.85 (0.1)

1.2 (1.9)

0.98 (0.15)

1.67 (2.9)

0.75 (0.1)

0.83 (0.2)

 ACR (mg albumin/gCr)

28 (26)

76 (79)

27 (29)

78 (77)

29 (23)

74 (82)

 uCreatinine (mg/L)

0.7 (0.4)

0.5 (0.2)

0.7 (0.4)

0.6 (0.2)

0.7 (0.4)

0.5 (0.2)

 eGFR (mL/min per 1.73 m2)

95 (21)

83 (26)

94 (17)

77 (28)

95 (23)

87 (24)

Medications

      

 No meds, n (%)

169 (63)

25 (9)

69 (62)

10 (9)

99 (63)

15 (9)

 ARB, n (%)

–

13 (5)

–

5 (5)

–

8 (5)

 ACEi, n (%)

2 (1)

30 (11)

2 (2)

12 (10)

3 (2)

18 (11)

 ARB/ACEi, n (%)

–

4 (1)

–

3 (3)

–

1 (1)

 β-adrenergic blockers, n (%)

2 (1)

19 (7)

–

11 (10)

–

8 (5)

 Calcium channel blockers, n (%)

–

1 (1)

–

–

–

1 (1)

 Diuretics, n (%)

–

4 (2)

–

–

–

4 (3)

 Diabetes medication, n (%)

1 (0.4)

80 (30)

1 (1)

35 (32)

–

46 (29)

  1. Data are expressed as mean (SD). ARB angiotensin-II type 1 receptor blocker, ACEi angiotensin-converting I enzyme inhibitors. Anti-diabetic medications include insulin, metformin, dipeptidyl peptidase-4 inhibitors, glucagon-like peptide 1 receptor agonist, sulfonylureas, and thiazolidinediones