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Table 3 Significant functions in the functional meta-analyses. The logarithm of the odds ratio (LOR), its confidence interval (LOR-CI), the adjusted p value, and the group in which the function was overexpressed are shown (W, women; M, men)

From: Hepatic steatosis and steatohepatitis: a functional meta-analysis of sex-based differences in transcriptomic studies

  GO ID Name LOR LOR-CI Adj. p value Group
Gene functional meta-analysis GO:0001012 RNA polymerase II regulatory region DNA binding 0.132 [0.079, 0.185] 0.008 W
GO:1900165 Negative regulation of interleukin-6 secretion -0.762 [-1.088, -0.437] 0.018 M
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding 0.131 [0.073, 0.188] 0.02 W
GO:0017166 Vinculin binding 0.511 [0.271, 0.75] 0.035 W
GO:0071352 Cellular response to interleukin-2 0.467 [0.248, 0.687] 0.035 W
GO:0090177 Establishment of planar polarity involved in neural tube closure -0.514 [-0.748, -0.279] 0.035 M
GO:0090178 Regulation of establishment of planar polarity involved in neural tube closure -0.523 [-0.768, -0.279] 0.035 M
GO:1901215 Negative regulation of neuron death 0.116 [0.06, 0.171] 0.043 W
GO:0070669 Response to interleukin-2 0.446 [0.23, 0.662] 0.046 W
Pathway functional meta-analysis GO:0098655 Cation transmembrane transport 0.194 [0.11, 0.279] 0.012 W
GO:0030001 Metal ion transport 0.141 [0.074, 0.208] 0.027 W
GO:1904062 Regulation of cation transmembrane transport 0.216 [0.119, 0.32] 0.027 W
GO:0098662 Inorganic cation transmembrane transport 0.186 [0.093, 0.278] 0.038 W
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Biology of Sex Differences

ISSN: 2042-6410

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