Fig. 2
From: Thyroid hormone: sex-dependent role in nervous system regulation and disease
Thyroid hormone receptors. In humans, there are three isoforms of THRα and three isoforms of THRβ. The human protein sequence was obtained from NCBI, and the protein domain was prepared using the protein illustrator software DOG 1.0 [45] (a). The DNA binding domain (DBD) is highly conserved among the receptors; however, the ligand binding domain (LBD) shows differences in sequence and length (b)