Table 4 Traits affected by protein restriction (PR) among studies that manipulated diet in multiple periods of gestation
Study | Na | Manipulation | Duration | Traits affectedin males | Traits affectedin females | Traits affectedin both sexes | Analysed sexes separatelyor tested interaction |
|---|---|---|---|---|---|---|---|
Wistar rats | |||||||
 Bellinger 2005 [21] | 5 | PR(9% vs 18%) | GD 0–7 | Hepatic | Behavioural | Body weight | Interaction |
GD 8–14 | None | Behavioural | None |  | |||
GD 15–22 | Hepatic | Behavioural | Body weight |  | |||
 Bellinger2006 [22] | 8–11 | PR(9% vs 18%) | GD 0–birth | Body weight; fat | Fat; behavioural | None | Interaction |
GD 0–7 | Body weight;fat; behavioural | Body weight; fat | None |  | |||
GD 8–14 | Body weight;behavioural | None | None |  | |||
GD 15–22 | Body weight;fat | Fat; behavioural | None |  | |||
 Chamson-Reig2006 [23] | 3–4 | PR(8% vs 20%) | GD 0–weaning | None | None | Pancreatic | Interaction |
GD 0–14 | None | Pancreatic | Pancreatic |  | |||
GD 8–14 | None | Pancreatic | Pancreatic |  | |||
GD 15–22 | Pancreatic | Pancreatic | Pancreatic |  | |||
 Mallinson2007 [33] | 11–13 | PR(9% vs 18%) | GD 0–birth | Muscular | None | None | Interaction |
GD 0–7 | Muscular | None | Muscular |  | |||
GD 8–14 | None | Muscular | Muscular |  | |||
GD 15–22 | None | None | Muscular |  | |||
Sprague-Dawley rats | |||||||
 Woods2004 [54] | 6–9 | PR(5% vs 19%) | GD 1–birth | Body weight;renal | None | Body weight; cardiovascular; renal | Sexes separately andinteraction |
GD 1–11 | None | None | None |  | |||
GD 11–birth | Body weight;renal | None | Cardiovascular |  | |||