Table 3 Traits affected by food restriction (FR) in the latter half of gestation in Sprague-Dawley rats
Study | Na | Manipulation | Duration | Traits affected in males | Traits affected in females | Traits affected in both sexes | Analysed sexes separately or tested interaction |
|---|---|---|---|---|---|---|---|
Choi 2007 [56] | 6 | FR (75%) | GD 10–birth | Hepatic | Hepatic | Birthweight; hepatic | Sexes separately |
Desai 2005 [57] | 12 | FR (50%) | GD 10–birth | None | None | Body weight | Not clear |
Desai 2007 [58] | 6 | FR (50%) | GD 10–birth | None | None | Body weight; fat; leptin; blood lipids; glucose; insulin; glucose tolerance test; behavioural | Not clear |
Gutierrez-Arzapalo 2018 [59] | 3–5 | FR (50%) | GD 11–birth | Cardiovascularb | Cardiovascularb | Birthweight; cardiovascular | Interaction |
Hemmings 2005 [60] | 8–11 | FR (40%) | GD 15–birth | Cardiovascular | Cardiovascular | Birthweight | Sexes separately |
Khorram 2011 [61] | 4–6 | FR (50%) | GD 10–birth | Corticosterone; adrenala | Adrenala | Body weight; adrenal | Sexes separately |
Lee 2013 [62] | 4 | FR (50%) | GD 10–birth | Body weight | None | Body weight; fat; blood lipids; leptin | Sexes separately |
Matveyenko 2010 [63] | 6 | FR (50%) | GD 11–21 | Body weight; pancreatic | None | Birthweight; pancreatic | Sexes separately |
Molle 2015 [64] | 6 | FR (50%) | GD 10–birth | Behaviouralb; brain | Behaviouralb | Behavioural; brain | Interaction |
Munoz-Valverde 2015 [65] | 12 | FR (50%) | GD 11–birth | None | None | Birthweight; cardiovascular; hepatic; fat; glucose | Sexes separately |
Paek 2015 [66] | 4 | FR (50%) | GD 10–birth | None | None | Birthweight; body weight; lung | Not clear |
RodrÃguez-RodrÃguez 2015 [67] | 6 | FR (50%) | GD 11–birth | Cardiovascular; oxidative status | None | Birthweight; oxidative status | Sexes separately |
RodrÃguez-RodrÃguez 2017 [68] | 5 | FR (50%) | GD 11–birth | Cardiovascularb | Cardiovascularb | Birthweight; cardiovascular | Interaction |
You 2015 [69] | 5 | FR (50%) | GD 10–birth | Hepatic; homocysteine | None | None | Sexes separately |