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Table 1 Patient characteristics stratified by gender

From: Age-dependent changes of gender disparities in nasopharyngeal carcinoma survival

Variable Total
(N = 9346)
Male
(N = 7026)
Female
(N = 2320)
P value
Age, mean ± SD 46.2 ± 11.2 46.7 ± 11.2 44.8 ± 11.3 < 0.001
Comorbidity     < 0.001
 No 7193 (77.0%) 5317 (75.7%) 1876 (80.9%)  
 Yes 2153 (23.0%) 1709 (24.3%) 444 (19.1%)  
Drinking status     < 0.001
 No 7919 (84.7%) 5619 (80.0%) 2300 (99.1%)  
 Yes 1427 (15.3%) 1407 (20.0%) 20 (0.9%)  
Smoking status     < 0.001
 No 5227 (55.9%) 2949 (42.0%) 2278 (98.2%)  
 Yes 4119 (44.1%) 4077 (58.0%) 42 (1.8%)  
BMI, mean ± SD 22.9 ± 3.24) 23.1 ± 3.19 22.2 ± 3.29 < 0.001
Histology type     0.714
 I 38 (0.41%) 28 (0.40%) 10 (0.43%)  
 II 494 (5.29%) 364 (5.18%) 130 (5.60%)  
 III 8814 (94.3%) 6634 (94.4%) 2180 (94.0%)  
VCA IgA     0.334
 0–40 1889 (20.2%) 1399 (19.9%) 490 (21.1%)  
 80–320 3071 (32.9%) 2303 (32.8%) 768 (33.1%)  
 > 320 4386 (46.9%) 3324 (47.3%) 1062 (45.8%)  
EA IgA     0.001
 0–10 3249 (34.8%) 2371 (33.7%) 878 (37.8%)  
 20–80 3951 (42.3%) 3009 (42.8%) 942 (40.6%)  
 > 80 2146 (23.0%) 1646 (23.4%) 500 (21.6%)  
T category     < 0.001
 T1 838 (8.97%) 653 (9.29%) 185 (7.97%)  
 T2 2388 (25.6%) 1756 (25.0%) 632 (27.2%)  
 T3 3930 (42.1%) 2875 (40.9%) 1055 (45.5%)  
 T4 2190 (23.4%) 1742 (24.8%) 448 (19.3%)  
N category     < 0.001
 N0 2078 (22.2%) 1616 (23.0%) 462 (19.9%)  
 N1 3659 (39.2%) 2664 (37.9%) 995 (42.9%)  
 N2 2908 (31.1%) 2188 (31.1%) 720 (31.0%)  
 N3 701 (7.50%) 558 (7.94%) 143 (6.16%)  
Clinical stage     < 0.001
 I 322 (3.45%) 258 (3.67%) 64 (2.76%)  
 II 1755 (18.8%) 1282 (18.2%) 473 (20.4%)  
 III 4518 (48.3%) 3305 (47.0%) 1213 (52.3%)  
 IV 2751 (29.4%) 2181 (31.0%) 570 (24.6%)  
Treatment modality     0.047
 RT alone 2805 (30.0%) 2136 (30.4%) 669 (28.8%)  
 CCRT 2263 (24.2%) 1662 (23.7%) 601 (25.9%)  
 IC + CCRT 4008 (42.9%) 3013 (42.9%) 995 (42.9%)  
 CCRT + AC 270 (2.89%) 215 (3.06%) 55 (2.37%)  
RT technique     0.172
 CRT 7042 (75.3%) 5319 (75.7%) 1723 (74.3%)  
 IMRT 2304 (24.7%) 1707 (24.3%) 597 (25.7%)  
Marital status     0.137
 Unmarried 429 (4.59%) 309 (4.40%) 120 (5.17%)  
 Married 8917 (95.4%) 6717 (95.6%) 2200 (94.8%)  
Employment     < 0.001
 Unemployed 817 (8.74%) 454 (6.46%) 363 (15.6%)  
 Employed 7918 (84.7%) 6159 (87.7%) 1759 (75.8%)  
 Retired 611 (6.54%) 413 (5.88%) 198 (8.53%)  
Education level     < 0.001
 Low 4284 (45.8%) 3025 (43.1%) 1259 (54.3%)  
 Medium 3089 (33.1%) 2423 (34.5%) 666 (28.7%)  
 High 1973 (21.1%) 1578 (22.5%) 395 (17.0%)  
  1. Abbreviations: SD standard deviation, BMI body mass index, VCA viral capsid antigen, IgA immunoglobulin A, EA early antigen, RT radiotherapy, CCRT concurrent chemo-radiotherapy, IC induction chemotherapy, AC adjuvant chemotherapy, CRT conventional radiotherapy, IMRT intensity-modulated radiotherapy