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Table 1 Patient characteristics stratified by gender

From: Age-dependent changes of gender disparities in nasopharyngeal carcinoma survival

Variable

Total

(N = 9346)

Male

(N = 7026)

Female

(N = 2320)

P value

Age, mean ± SD

46.2 ± 11.2

46.7 ± 11.2

44.8 ± 11.3

< 0.001

Comorbidity

   

< 0.001

 No

7193 (77.0%)

5317 (75.7%)

1876 (80.9%)

 

 Yes

2153 (23.0%)

1709 (24.3%)

444 (19.1%)

 

Drinking status

   

< 0.001

 No

7919 (84.7%)

5619 (80.0%)

2300 (99.1%)

 

 Yes

1427 (15.3%)

1407 (20.0%)

20 (0.9%)

 

Smoking status

   

< 0.001

 No

5227 (55.9%)

2949 (42.0%)

2278 (98.2%)

 

 Yes

4119 (44.1%)

4077 (58.0%)

42 (1.8%)

 

BMI, mean ± SD

22.9 ± 3.24)

23.1 ± 3.19

22.2 ± 3.29

< 0.001

Histology type

   

0.714

 I

38 (0.41%)

28 (0.40%)

10 (0.43%)

 

 II

494 (5.29%)

364 (5.18%)

130 (5.60%)

 

 III

8814 (94.3%)

6634 (94.4%)

2180 (94.0%)

 

VCA IgA

   

0.334

 0–40

1889 (20.2%)

1399 (19.9%)

490 (21.1%)

 

 80–320

3071 (32.9%)

2303 (32.8%)

768 (33.1%)

 

 > 320

4386 (46.9%)

3324 (47.3%)

1062 (45.8%)

 

EA IgA

   

0.001

 0–10

3249 (34.8%)

2371 (33.7%)

878 (37.8%)

 

 20–80

3951 (42.3%)

3009 (42.8%)

942 (40.6%)

 

 > 80

2146 (23.0%)

1646 (23.4%)

500 (21.6%)

 

T category

   

< 0.001

 T1

838 (8.97%)

653 (9.29%)

185 (7.97%)

 

 T2

2388 (25.6%)

1756 (25.0%)

632 (27.2%)

 

 T3

3930 (42.1%)

2875 (40.9%)

1055 (45.5%)

 

 T4

2190 (23.4%)

1742 (24.8%)

448 (19.3%)

 

N category

   

< 0.001

 N0

2078 (22.2%)

1616 (23.0%)

462 (19.9%)

 

 N1

3659 (39.2%)

2664 (37.9%)

995 (42.9%)

 

 N2

2908 (31.1%)

2188 (31.1%)

720 (31.0%)

 

 N3

701 (7.50%)

558 (7.94%)

143 (6.16%)

 

Clinical stage

   

< 0.001

 I

322 (3.45%)

258 (3.67%)

64 (2.76%)

 

 II

1755 (18.8%)

1282 (18.2%)

473 (20.4%)

 

 III

4518 (48.3%)

3305 (47.0%)

1213 (52.3%)

 

 IV

2751 (29.4%)

2181 (31.0%)

570 (24.6%)

 

Treatment modality

   

0.047

 RT alone

2805 (30.0%)

2136 (30.4%)

669 (28.8%)

 

 CCRT

2263 (24.2%)

1662 (23.7%)

601 (25.9%)

 

 IC + CCRT

4008 (42.9%)

3013 (42.9%)

995 (42.9%)

 

 CCRT + AC

270 (2.89%)

215 (3.06%)

55 (2.37%)

 

RT technique

   

0.172

 CRT

7042 (75.3%)

5319 (75.7%)

1723 (74.3%)

 

 IMRT

2304 (24.7%)

1707 (24.3%)

597 (25.7%)

 

Marital status

   

0.137

 Unmarried

429 (4.59%)

309 (4.40%)

120 (5.17%)

 

 Married

8917 (95.4%)

6717 (95.6%)

2200 (94.8%)

 

Employment

   

< 0.001

 Unemployed

817 (8.74%)

454 (6.46%)

363 (15.6%)

 

 Employed

7918 (84.7%)

6159 (87.7%)

1759 (75.8%)

 

 Retired

611 (6.54%)

413 (5.88%)

198 (8.53%)

 

Education level

   

< 0.001

 Low

4284 (45.8%)

3025 (43.1%)

1259 (54.3%)

 

 Medium

3089 (33.1%)

2423 (34.5%)

666 (28.7%)

 

 High

1973 (21.1%)

1578 (22.5%)

395 (17.0%)

 
  1. Abbreviations: SD standard deviation, BMI body mass index, VCA viral capsid antigen, IgA immunoglobulin A, EA early antigen, RT radiotherapy, CCRT concurrent chemo-radiotherapy, IC induction chemotherapy, AC adjuvant chemotherapy, CRT conventional radiotherapy, IMRT intensity-modulated radiotherapy