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Table 4 Subgroup analysis of the association between VFA-to-LMM ratio and hyperuricemia according to menopausal status

From: The visceral fat area to leg muscle mass ratio is significantly associated with the risk of hyperuricemia among women: a cross-sectional study

Menopausal status

Model 1a

Model 2

Model 3

Model 4

Pre-menopausal

 Quartile 1

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Quartile 2

3.50 (1.06, 15.75)

3.65 (1.10, 16.47)

3.63 (1.04, 17.10)

2.78 (0.79, 13.06)

 Quartile 3

5.01 (1.61, 21.95)

5.30 (1.70, 23.27)

4.62 (1.36, 21.65)

2.84 (0.78, 13.74)

 Quartile 4

12.04 (4.21, 50.78)

12.97 (4.50, 54.99)

8.25 (2.52, 37.99)

3.61 (0.90, 18.86)

 P for trendb

< .0001

< .0001

0.0005

0.1503

Post-menopausal

 Quartile 1

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Quartile 2

2.52 (1.29, 5.19)

2.50 (1.27, 5.18)

2.18 (1.05, 4.73)

1.79 (0.84, 3.96)

 Quartile 3

2.36 (1.20, 4.89)

2.25 (1.14, 4.69)

1.85 (0.88, 4.03)

1.35 (0.61, 3.09)

 Quartile 4

3.71 (1.95, 7.51)

3.43 (1.79, 6.99)

3.33 (1.64, 7.13)

1.94 (0.80, 4.81)

 P for trend

0.0003

0.0010

0.0029

0.3130

  1. Values are ORs (95% CIs) unless otherwise indicated. VFA visceral fat area, LMM leg muscle mass
  2. aModel 1: adjusted for age; model 2: adjusted for age, drinking status, exercise frequency, and history of diseases (hypertension and diabetes); model 3: additionally adjusted for systolic blood pressure, diastolic blood pressure, alanine aminotransferase, fasting plasma glucose, total cholesterol, triglycerides, low-density lipoprotein and high-density lipoprotein cholesterol, and creatinine. model 4: adjusted for model 3 + BMI
  3. bP values for linear trends were calculated using the median value of quartiles of VFA-to-LMM ratio