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Table 3 Odds ratio with 95% confidence interval for the association between VFA-to-LMM ratio and hyperuricemia according to sex

From: The visceral fat area to leg muscle mass ratio is significantly associated with the risk of hyperuricemia among women: a cross-sectional study

Quartiles of VFA-to-LMM ratio

Model 1a

Model 2

Model 3

Model 4

Male

 Quartile 1

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Quartile 2

1.25 (0.86, 1.82)

1.21 (0.83, 1.77)

0.91 (0.60, 1.36)

0.75 (0.49, 1.15)

 Quartile 3

1.58 (1.09, 2.31)

1.51 (1.03, 2.21)

1.03 (0.67, 1.57)

0.79 (0.50, 1.25)

 Quartile 4

2.73 (1.89, 3.95)

2.49 (1.70, 3.65)

1.60 (1.03, 2.49)

0.97 (0.55, 1.70)

 P for trendb

< .0001

< .0001

0.0180

0.9563

Female

 Quartile 1

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Quartile 2

2.66 (1.23, 6.42)

2.58 (1.19, 6.23)

2.13 (0.96, 5.21)

1.68 (0.75, 4.17)

 Quartile 3

5.20 (2.55, 12.10)

4.95 (2.41, 11.54)

3.74 (1.75, 8.95)

2.42 (1.09, 6.01)

 Quartile 4

8.25 (4.05, 19.14)

7.37 (3.59, 17.24)

5.22 (2.44, 12.56)

2.57 (1.06, 6.77)

 P for trend

< .0001

< .0001

< .0001

0.0454

  1. Values are ORs (95% CIs) unless otherwise indicated. VFA, visceral fat area; LMM, leg muscle mass.
  2. aModel 1: adjusted for age; model 2: adjusted for age, smoking status (for men), menopause status (for women), drinking status, exercise frequency, and history of diseases (hypertension and diabetes); model 3: additionally adjusted for systolic blood pressure, diastolic blood pressure, alanine aminotransferase, fasting plasma glucose, total cholesterol, triglycerides, low-density lipoprotein and high-density lipoprotein cholesterol, and creatinine; model 4: adjusted for model 3 + BMI
  3. bP values for linear trends were calculated using the median value of quartiles of VFA-to-LMM ratio
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Biology of Sex Differences

ISSN: 2042-6410

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