|
Characteristics
|
Men (n = 1469)
|
Pa
|
Women (n = 1924)
|
P
|
|---|
|
Non-hyperuricemia (n = 1139)
|
Hyperuricemia (n = 330)
|
Non-hyperuricemia (n = 1753)
|
Hyperuricemia (n = 171)
|
|---|
|
Age, years
|
47.9 ± 15.7
|
44.4 ± 14.6
|
0.0002
|
44.0 ± 14.5
|
54.4 ± 16.1
|
< .0001
|
|
BMI, kg/m2
|
25.4 ± 3.2
|
27.0 ± 3.5
|
< .0001
|
22.8 ± 3.2
|
26.0 ± 3.9
|
< .0001
|
|
SBP, mmHg
|
127.0 ± 16.8
|
127.8 ± 15.4
|
0.4377
|
117.3 ± 18.1
|
129.8 ± 19.3
|
< .0001
|
|
DBP, mmHg
|
80.2 ± 10.0
|
83.4 ± 10.0
|
< .0001
|
75.4 ± 9.7
|
79.1 ± 11.5
|
< .0001
|
|
VFA, cm2
|
90.7 ± 32.8
|
104.9 ± 36.6
|
< .0001
|
95.1 ± 35.4
|
129.1 ± 41.0
|
< .0001
|
|
LMM, kg
|
17.4 ± 2.2
|
18.0 ± 2.2
|
< .0001
|
12.3 ± 1.6
|
12.5 ± 1.8
|
0.1409
|
|
ALT, units/L
|
21.6 (15.3, 31.6)b
|
27.3 (18.8, 45.5)
|
< .0001
|
13.8 (10.0, 19.6)
|
18.3 (13.6, 26.0)
|
< .0001
|
|
FPG, mmol/L
|
5.3 (4.9, 5.9)
|
5.2 (5.0, 5.7)
|
0.3329
|
5.1 (4.8, 5.4)
|
5.6 (5.1, 6.5)
|
< .0001
|
|
TC, mmol/L
|
5.0 ± 0.9
|
5.2 ± 0.9
|
< .0001
|
5.1 ± 1.0
|
5.8 ± 1.2
|
< .0001
|
|
TG, mmol/L
|
1.3 (0.9, 1.8)
|
1.7 (1.2, 2.3)
|
< .0001
|
1.0 (0.7, 1.4)
|
1.6 (1.1, 2.2)
|
< .0001
|
|
LDL-C, mmol/L
|
2.6 ± 0.5
|
2.8 ± 0.5
|
< .0001
|
2.7 ± 0.6
|
3.1 ± 0.7
|
< .0001
|
|
HDL-C, mmol/L
|
1.3 ± 0.2
|
1.3 ± 0.2
|
< .0001
|
1.6 ± 0.3
|
1.5 ± 0.3
|
< .0001
|
|
SUA, μmol/L
|
336.0 ± 50.3
|
468.7 ± 47.1
|
< .0001
|
260.4 ± 45.8
|
395.3 ± 38.0
|
< .0001
|
|
Creatinine, μmol/L
|
74.7 ± 10.0
|
79.8 ± 11.7
|
< .0001
|
55.6 ± 7.7
|
61.5 ± 11.6
|
< .0001
|
|
Smoking, n (%)
|
247 (21.7)
|
69 (20.9)
|
0.7624
|
13 (0.7)
|
0 (0.0)
|
0.6208
|
|
Drinking, n (%)
|
459 (40.3)
|
129 (39.1)
|
0.6934
|
107 (6.1)
|
5 (2.9)
|
0.1275
|
|
Exercise, n (%)
|
|
Never
|
285 (25.0)
|
95 (28.8)
|
0.1689
|
461 (26.3)
|
50 (29.2)
|
0.4057
|
|
Occasional
|
380 (33.4)
|
124 (37.6)
|
0.1557
|
733 (41.8)
|
63 (36.8)
|
0.2076
|
|
Regular
|
474 (41.6)
|
111 (33.6)
|
0.0091
|
559 (31.9)
|
58 (33.9)
|
0.5872
|
|
Hypertension, n (%)
|
355 (31.2)
|
114 (34.6)
|
0.2465
|
288 (16.4)
|
71 (41.5)
|
< .0001
|
|
Diabetes, n (%)
|
124 (10.9)
|
28 (8.5)
|
0.2071
|
69 (3.9)
|
26 (15.2)
|
< .0001
|
|
Dyslipidemia, n (%)
|
258 (22.7)
|
131 (39.7)
|
< .0001
|
316 (18.0)
|
76 (44.4)
|
< .0001
|
|
NAFLD, n (%)
|
473 (41.5)
|
211 (63.9)
|
< .0001
|
405 (23.1)
|
116 (67.8)
|
< .0001
|
|
Obesity, n (%)
|
232 (20.4)
|
122 (37.0)
|
< .0001
|
123 (7.0)
|
36 (21.1)
|
< .0001
|
|
History of diseases, n (%)
|
|
Hypertension
|
367 (32.2)
|
111 (33.6)
|
0.6290
|
317 (18.1)
|
75 (43.9)
|
< .0001
|
|
Diabetes
|
116 (10.2)
|
23 (7.0)
|
0.0789
|
84 (4.8)
|
25 (14.6)
|
< .0001
|
|
CHD
|
68 (6.0)
|
18 (5.5)
|
0.7254
|
53 (3.0)
|
19 (11.1)
|
< .0001
|
- BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, VFA visceral fat area, LMM leg muscle mass, ALT alanine aminotransferase, FPG fasting plasma glucose, TC total cholesterol, TG triglycerides, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, SUA serum uric acid, NAFLD non-alcoholic fatty liver diseases, CHD coronary heart disease
- Continuous variables are expressed as means ± standard deviation (SD) and categorical variables are expressed as percentages unless otherwise indicated
- aAnalysis of variance or chi-square test where appropriate
- bData are expressed as medians (interquartile range)
