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Table 1 Characteristics of the study population according to sex and hyperuricemia status

From: The visceral fat area to leg muscle mass ratio is significantly associated with the risk of hyperuricemia among women: a cross-sectional study

Characteristics

Men (n = 1469)

Pa

Women (n = 1924)

P

Non-hyperuricemia (n = 1139)

Hyperuricemia (n = 330)

Non-hyperuricemia (n = 1753)

Hyperuricemia (n = 171)

Age, years

47.9 ± 15.7

44.4 ± 14.6

0.0002

44.0 ± 14.5

54.4 ± 16.1

< .0001

BMI, kg/m2

25.4 ± 3.2

27.0 ± 3.5

< .0001

22.8 ± 3.2

26.0 ± 3.9

< .0001

SBP, mmHg

127.0 ± 16.8

127.8 ± 15.4

0.4377

117.3 ± 18.1

129.8 ± 19.3

< .0001

DBP, mmHg

80.2 ± 10.0

83.4 ± 10.0

< .0001

75.4 ± 9.7

79.1 ± 11.5

< .0001

VFA, cm2

90.7 ± 32.8

104.9 ± 36.6

< .0001

95.1 ± 35.4

129.1 ± 41.0

< .0001

LMM, kg

17.4 ± 2.2

18.0 ± 2.2

< .0001

12.3 ± 1.6

12.5 ± 1.8

0.1409

ALT, units/L

21.6 (15.3, 31.6)b

27.3 (18.8, 45.5)

< .0001

13.8 (10.0, 19.6)

18.3 (13.6, 26.0)

< .0001

FPG, mmol/L

5.3 (4.9, 5.9)

5.2 (5.0, 5.7)

0.3329

5.1 (4.8, 5.4)

5.6 (5.1, 6.5)

< .0001

TC, mmol/L

5.0 ± 0.9

5.2 ± 0.9

< .0001

5.1 ± 1.0

5.8 ± 1.2

< .0001

TG, mmol/L

1.3 (0.9, 1.8)

1.7 (1.2, 2.3)

< .0001

1.0 (0.7, 1.4)

1.6 (1.1, 2.2)

< .0001

LDL-C, mmol/L

2.6 ± 0.5

2.8 ± 0.5

< .0001

2.7 ± 0.6

3.1 ± 0.7

< .0001

HDL-C, mmol/L

1.3 ± 0.2

1.3 ± 0.2

< .0001

1.6 ± 0.3

1.5 ± 0.3

< .0001

SUA, μmol/L

336.0 ± 50.3

468.7 ± 47.1

< .0001

260.4 ± 45.8

395.3 ± 38.0

< .0001

Creatinine, μmol/L

74.7 ± 10.0

79.8 ± 11.7

< .0001

55.6 ± 7.7

61.5 ± 11.6

< .0001

Smoking, n (%)

247 (21.7)

69 (20.9)

0.7624

13 (0.7)

0 (0.0)

0.6208

Drinking, n (%)

459 (40.3)

129 (39.1)

0.6934

107 (6.1)

5 (2.9)

0.1275

Exercise, n (%)

 Never

285 (25.0)

95 (28.8)

0.1689

461 (26.3)

50 (29.2)

0.4057

 Occasional

380 (33.4)

124 (37.6)

0.1557

733 (41.8)

63 (36.8)

0.2076

 Regular

474 (41.6)

111 (33.6)

0.0091

559 (31.9)

58 (33.9)

0.5872

Hypertension, n (%)

355 (31.2)

114 (34.6)

0.2465

288 (16.4)

71 (41.5)

< .0001

Diabetes, n (%)

124 (10.9)

28 (8.5)

0.2071

69 (3.9)

26 (15.2)

< .0001

Dyslipidemia, n (%)

258 (22.7)

131 (39.7)

< .0001

316 (18.0)

76 (44.4)

< .0001

NAFLD, n (%)

473 (41.5)

211 (63.9)

< .0001

405 (23.1)

116 (67.8)

< .0001

Obesity, n (%)

232 (20.4)

122 (37.0)

< .0001

123 (7.0)

36 (21.1)

< .0001

History of diseases, n (%)

 Hypertension

367 (32.2)

111 (33.6)

0.6290

317 (18.1)

75 (43.9)

< .0001

 Diabetes

116 (10.2)

23 (7.0)

0.0789

84 (4.8)

25 (14.6)

< .0001

 CHD

68 (6.0)

18 (5.5)

0.7254

53 (3.0)

19 (11.1)

< .0001

  1. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, VFA visceral fat area, LMM leg muscle mass, ALT alanine aminotransferase, FPG fasting plasma glucose, TC total cholesterol, TG triglycerides, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, SUA serum uric acid, NAFLD non-alcoholic fatty liver diseases, CHD coronary heart disease
  2. Continuous variables are expressed as means ± standard deviation (SD) and categorical variables are expressed as percentages unless otherwise indicated
  3. aAnalysis of variance or chi-square test where appropriate
  4. bData are expressed as medians (interquartile range)
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Biology of Sex Differences

ISSN: 2042-6410

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